The binding of sequence-specific RNA-interacting proteins, such as the bacteriophage MS2
or PP7 coat proteins, to their corresponding target sequences has been extremely useful …

Allele-specific protein-RNA binding is an essential aspect that may reveal functional genetic
variants (GVs) mediating post-transcriptional regulation. Recently, genome-wide detection of …

Many protein–protein and protein–nucleic acid interactions have been experimentally
characterized, whereas RNA–RNA interactions have generally only been predicted …

Abstract eIF4E-binding proteins (4E-BPs) regulate translation of mRNAs in eukaryotes.
However the extent to which specific mRNA targets are regulated by 4E-BPs remains …

The control of mammalian mRNA turnover and translation has been linked almost
exclusively to specific cis-elements within the 5'-and 3'-untranslated regions (UTRs) of the …

Protein localization within cells can be achieved by the targeting and localized translation of
mRNA. Yet, our understanding of the dynamics of mRNA targeting and protein localization …

Signal recognition particle (SRP) RNA exhibits significant primary sequence conservation
only in domain IV, a bulged hairpin capped by a GNRA (N, any nucleotide; R, purine) …

RNA–protein interactions are pervasive. The specificity of these interactions dictates which
RNAs are controlled by what protein. Here we describe a class of revolutionary new …

Post‐transcriptional mRNA modifications play diverse roles in gene expression and RNA
function. In many cases, RNA modifications function by altering how cellular machinery such …

Eukaryotic cells determine the final protein output of their genetic program not only by
controlling transcription but also by regulating the localization, translation and turnover rates …