Problems With Understanding Chlamydia trachomatis Immunology

RC Brunham - The Journal of Infectious Diseases, 2022 - academic.oup.com
The payoff for understanding Chlamydia trachomatis immunology is the development of a
vaccine. Two lines of research have contributed to our current understanding of C …

Immunology of Chlamydia infection: implications for a Chlamydia trachomatis vaccine

RC Brunham, J Rey-Ladino - Nature reviews immunology, 2005 - nature.com
Sexually transmitted Chlamydia trachomatis infections are a serious public-health problem.
With more than 90 million new cases occurring annually, C. trachomatis is the most common …

Human Immune Response and Chlamydia trachomatis Infection

D Kunimoto, RC Brunham - Reviews of infectious diseases, 1985 - academic.oup.com
Chlamydia trachomatis is a prevalent pathogen in human populations in both developing
and developed areas of the globe. Disease burden is heavy, since both acute and chronic …

Immunity to Chlamydia trachomatis

RC Brunham - The Journal of infectious diseases, 2013 - academic.oup.com
In this issue of the Journal, Geisler and colleagues [1] report convincing epidemiological
evidence that cervical infection with Chlamydia trachomatis produces immunity in at least a …

Vaccines for Chlamydia trachomatis infections.

LM de la Maza, EM Peterson - Current opinion in investigational …, 2002 - europepmc.org
Members of the genus, Chlamydia, are obligate intracellular bacteria that have a unique
developmental cycle. These organisms are widespread in nature and are common human …

[HTML][HTML] Chlamydia trachomatis: Cell biology, immunology and vaccination

SM Murray, PF McKay - Vaccine, 2021 - Elsevier
Chlamydia trachomatis is the causative agent of a highly prevalent sexually transmitted
bacterial disease and is associated with a number of severe disease complications. Current …

[PDF][PDF] Chlamydia trachomatis genital infection: immunity and prospects for vaccine development

MRC Vergara, AJ Buendia Marin, L del Rio Alonzo… - …, 2005 - researchgate.net
Chlamydia trachomatis is an obligate intracellular bacteria characterized by a biphasic
development cycle of replication. The organism is now recognized the major cause of …

Murine Chlamydia trachomatis Genital Infection Is Unaltered by Depletion of CD4+ T cells and Diminished Adaptive Immunity

SG Morrison, CM Farris, GL Sturdevant… - Journal of Infectious …, 2011 - academic.oup.com
Chlamydia muridarum and Chlamydia trachomatis mouse models of genital infection have
been used to study chlamydial immunity and vaccine development. To assess the protective …

Immunity, immunopathology, and human vaccine development against sexually transmitted Chlamydia trachomatis

J Rey-Ladino, AGP Ross, AW Cripps - Human Vaccines & …, 2014 - Taylor & Francis
This review examines the immunity, immunopathology, and contemporary problems of
vaccine development against sexually transmitted Chlamydia trachomatis. Despite improved …

T Lymphocyte Immunity in Host Defence against Chlamydia trachomatis and Its Implication for Vaccine Development

X Yang, RC Brunham - Canadian Journal of Infectious …, 1998 - Wiley Online Library
Chlamydia trachomatis is an obligate intracellular bacterial pathogen that causes several
significant human infectious diseases, including trachoma, urethritis, cervicitis and …