Safety assessment and gastrointestinal retention of orally administered cerium oxide nanoparticles in rats

HY Han, BK Kim, J Rho, SM Park, MS Choi, S Kim… - Scientific Reports, 2024 - nature.com
Abstract Cerium oxide nanoparticles (CeO2 NPs, NM-212) are well-known for their catalytic
properties and antioxidant potential, and have many applications in various industries, drug …

Toxicity and tissue distribution of cerium oxide nanoparticles in rats by two different routes: single intravenous injection and single oral administration

K Park, J Park, H Lee, J Choi, WJ Yu, J Lee - Archives of pharmacal …, 2018 - Springer
Toxicity and target organ distribution of cerium oxide nanoparticles (CeNPs) were
investigated via single intravenous injection and single oral administration, respectively …

Effects of cerium oxide nanoparticles on differentiated/undifferentiated human intestinal Caco-2 cells

L Vila, A García-Rodríguez, C Cortés… - Chemico-Biological …, 2018 - Elsevier
Since ingestion constitute one of the main routes of nanoparticles (NPs) exposure, intestinal
cells seems to be a suitable choice to evaluate their potential harmful effects. Caco-2 cells …

[HTML][HTML] Comparison of biodistribution of cerium oxide nanoparticles after repeated oral administration by gavage or snack in Sprague Dawley rats

T Berthing, E Holmfred, J Vidmar, N Hadrup… - Environmental …, 2022 - Elsevier
The rate of translocation of ingested nanoparticles (NPs) and how the uptake is affected by a
food matrix are key aspects of health risk assessment. In this study, female Sprague Dawley …

Intratracheal instillation of cerium oxide nanoparticles induces hepatic toxicity in male Sprague-Dawley rats

SK Nalabotu, MB Kolli, WE Triest, JY Ma… - International journal …, 2011 - Taylor & Francis
Background Cerium oxide (CeO2) nanoparticles have been posited to have both beneficial
and toxic effects on biological systems. Herein, we examine if a single intratracheal …

Uptake of cerium oxide nanoparticles and its influence on functions of mouse leukemic monocyte macrophages

X Zhou, B Wang, P Jiang, Y Chen, Z Mao… - Journal of Nanoparticle …, 2015 - Springer
Exposure of the CeO 2 nanoparticles (NPs) causes a public concern on their potential health
risk due to their wide applications in the fields of fuel additive, commodities, pharmaceutical …

Safety assessment of cerium oxide nanoparticles: combined repeated-dose toxicity with reproductive/developmental toxicity screening and biodistribution in rats

J Lee, JS Jeong, SY Kim, SJ Lee, YJ Shin, WJ Im… - …, 2020 - Taylor & Francis
Abstract Cerium oxide nanoparticles (CeO2 NPs) are widely used in various commercial
applications because of their characteristic properties. People can be easily exposed to …

CeO2 nanoparticles synthesized through green chemistry are biocompatible: In vitro and in vivo assessment

S Naz, STB Kazmi, M Zia - Journal of biochemical and …, 2019 - Wiley Online Library
Widespread use of cerium oxide (CeO2) nanoparticles (NPs) is found in almost all areas of
research due to their distinctive properties. CeO2 NPs synthesized via green chemistry have …

Antioxidant and toxicity studies of biosynthesized cerium oxide nanoparticles in rats

MB Khorrami, HR Sadeghnia, A Pasdar… - International journal …, 2019 - Taylor & Francis
Purpose The purpose of this study was to investigate the acute toxic potential of cerium
oxide nanoparticles (CNPs) synthesized by pullulan in adult male Wistar rats. Patients and …

Toxicity study of cerium oxide nanoparticles in human neuroblastoma cells

M Kumari, SP Singh, S Chinde… - … journal of toxicology, 2014 - journals.sagepub.com
The present study consisted of cytotoxic, genotoxic, and oxidative stress responses of
human neuroblastoma cell line (IMR32) following exposure to different doses of cerium …