[HTML][HTML] LncRNAs and the angiogenic switch in cancer: clinical significance and therapeutic opportunities

P Mabeta, R Hull, Z Dlamini - Genes, 2022 - mdpi.com
Angiogenesis is one of the hallmarks of cancer, and the establishment of new blood vessels
is vital to allow for a tumour to grow beyond 1–2 mm in size. The angiogenic switch is the …

Roles of lncRNAs in cancer: Focusing on angiogenesis

KT Jin, JY Yao, XL Fang, H Di, YY Ma - Life sciences, 2020 - Elsevier
Approximately 98% of the human genome consists of non-coding sequences that are
classified into two classes by size: small non-coding RNAs (≤ 200 nucleotides) and long …

[HTML][HTML] The role of long non-coding RNAs in angiogenesis and anti-angiogenic therapy resistance in cancer

J Liu, Q Zhang, D Yang, F Xie, Z Wang - Molecular Therapy-Nucleic Acids, 2022 - cell.com
It is well known that long non-coding RNAs (lncRNAs) play an important role in the
regulation of tumor genesis and development. They can modulate gene expression of …

[HTML][HTML] Involvement of long non-coding RNAs (lncRNAs) in tumor angiogenesis

J Teppan, DA Barth, F Prinz, K Jonas, M Pichler… - Non-coding RNA, 2020 - mdpi.com
Long non-coding RNAs (lncRNAs) are defined as non-protein coding transcripts with a
minimal length of 200 nucleotides. They are involved in various biological processes such …

Biogenesis, classification, and role of LncRNAs in tumor angiogenesis: a focus on tumor and its neighbouring cells, and interaction with miRNAs

S Vimalraj, R Subramanian - Process Biochemistry, 2022 - Elsevier
Angiogenesis is crucial for tumor development and metastasis. Regulation of tumor-
associated angiogenesis appears to be a promising strategy for limiting the growth of …

Angiogenic lncRNAs: A potential therapeutic target for ischaemic heart disease

ZM Xu, F Huang, WQ Huang - Life sciences, 2018 - Elsevier
Abstract Long noncoding RNAs (LncRNAs) are involved in biological processes and the
pathology of diseases and represent an important biomarker or therapeutic target for …

[HTML][HTML] Long noncoding RNAs, emerging and versatile regulators of tumor-induced angiogenesis

J Zhao, L Li, ZY Han, ZX Wang… - American journal of cancer …, 2019 - ncbi.nlm.nih.gov
Angiogenesis is an essential step in maintaining tumor growth and facilitating metastasis.
The regulatory mechanisms of tumor-induced angiogenesis are extremely complicated, and …

LncRNA as a therapeutic target for angiogenesis

MM Kumar, R Goyal - Current topics in medicinal chemistry, 2017 - ingentaconnect.com
Background: Out of 3 billion base pairs in human genome only~ 2% code for proteins; and
out of 180,000 transcripts in human cells, about 20,000 code for protein, remaining 160,000 …

Long noncoding RNAs: emerging regulators of tumor angiogenesis

SR Sheng, JS Wu, YL Tang, XH Liang - Future Oncology, 2017 - Taylor & Francis
Long noncoding RNAs (lncRNAs) participate in multiple biological processes especially
human diseases, of which, tumor seems to be one of the most significant. Angiogenesis has …

Roles of long non-coding RNAs in angiogenesis-related diseases: Focusing on non-neoplastic aspects

D Li, L Liu, X He, N Wang, R Sun, X Li, T Yu, X Chu - Life sciences, 2023 - Elsevier
Angiogenesis is a key process in organ and tissue morphogenesis, as well as growth during
human development, and is coordinated by pro-and anti-angiogenic factors. When this …