In recent years, the incidence of non-communicable diseases (NCD) normally associated
with advanced age has begun presenting in younger populations. This has resulted in a …

Introduction: Aging is a normal, inevitable, irreversible and progressive process which is
driven by internal and external factors. Oxidative stress, that is the imbalance between …

Considering that the phenomenon of accelerated ageing contributes to early onset of
various chronic diseases, modelling of the relevant dysregulated systems or responses is …

There is still ongoing controversy about the oxidative stress theory of aging, particularly in
mammals, after a significant number of studies have been conducted to test this theory …

Rheumatoid arthritis is prevalent in more than 1% of the global population, with the highest
occurrence between ages 35 and 50, which places a huge burden on the economy. Drug …

Oxidative damage accumulation in macromolecules has been considered as causative of
cellular damage and pathology. Considering early observations of Gershman that oxygen …

While oxidative stress is implicated in aging, the impact of oxidative stress on aging in the
peripheral nervous system is not well understood. To determine a potential mechanism for …

Oxidative stress-mediated damage to functional macromolecules followed by their
accumulation has been reported as a major factor behind aging and related consequences …

Longevity is a complex and multifactorial process in which the balance in redox state has an
important role. The production of reactive oxygen/reactive nitrogen species (ROS/RNS) at …

Aging researches have experienced an unprecedented advance over recent years. The
comprehension of process leading to age-associated alterations is at moment of the highest …