Obesity is associated with many adverse health effects, such as an increased
cardiometabolic risk. Despite higher adiposity for a given BMI, premenopausal women are at …

The prevalence of obesity has dramatically increased over the past decade along with the
cardiovascular and other health risks it encompasses. Adipose tissue, which is distributed in …

Sex differences in body fat distribution, glucose homeostasis, insulin signaling, ectopic fat
accumulation, and lipid metabolism during normal growth and in response to hormonal or …

This review focuses on the human genetics, epidemiology, and molecular pathophysiology
of sex differences in central obesity, adipose distribution, and related cardiometabolic …

The NIH has recently highlighted the importance of sexual dimorphisms and has mandated
inclusion of both sexes in clinical trials and basic research. In this review we highlight new …

Adipose tissue is a complex and multi-faceted organ. It responds dynamically to internal and
external stimuli, depending on the developmental stage and activity of the organism. The …

Gender and biological sex impact the pathogenesis of numerous diseases, including
metabolic disorders such as diabetes. In most parts of the world, diabetes is more prevalent …

It is well documented that the metabolic syndrome predisposes patients to increased
cardiovascular risk. Emerging data indicates that cardiovascular risk conferred by metabolic …

BACKGROUND: The metabolic syndrome is a clinical condition characterized by the
presence of multiple interrelated risk factors for type 2 diabetes and cardiovascular disease …

Abstract Purpose of Review As the ongoing epidemic of adult and childhood obesity grows,
it puts a greater burden on individuals and the healthcare system due to increased …