Aims To report longitudinal quality of life (QoL) outcomes and survival in patients with poor-
prognosis high-grade glioma (HGG) treated with palliative hypofractionated radiotherapy …

Purpose/Objective (s) The prognosis of high-grade glioma (HGG) in elderly patients (> 65
years) and/or those with low Karnofsky performance status (KPS≤ 60) is generally poor with …

Purpose: To assess the survival benefit of palliative hypofractionated radiotherapy in
patients with poor prognosis high grade glioma by a matched comparison to conventionally …

Materials and Methods: The resource-sparing hypoRT regimen was delivered once weekly
(5Gy/fraction) for seven fractions to a total dose of 35Gy in seven fractions over six weeks …

High grade gliomas (HGG) include World Health Organization (WHO) grade III anaplastic
astrocytoma (AA) and WHO grade IV glioblastoma (GBM). As genomic alterations are …

Simple Summary Historically, frail patients who were older and showed poor performance
status have been treated with a total dose of 40–45 Gy in 15 fractions, 34 Gy in 10 fractions …

Background/Aim: Hypo-fractionated radiotherapy (HF-RT) is increasingly used for elderly
and frail glioblastoma patients. In countries with limited radiotherapy capacities, HF-RT is …

PURPOSE: To evaluate the outcome for elderly or younger poor prognosis glioblastoma
patients treated with hypofractionated radiotherapy (HypoRT). METHODS AND MATERIALS …

Background The current treatment for newly diagnosed glioblastoma consists of surgery
followed by conventional radiotherapy (CRT) with concomitant and adjuvant chemotherapy …

Background Glioblastoma (GBM) poses therapeutic challenges due to its aggressive nature,
particularly for patients with poor functional status and/or advanced disease …