A nucleoside diphosphate-linked moiety X (Nudix) hydrolase-like gene, YSA1, has been
identified as one of the gromwell plant extract-responsive genes in Cryptococcus …

Scedosporium boydii is an opportunistic filamentous fungus which may be responsible for a
large variety of infections in both immunocompetent and immunocompromised individuals …

Upon ingestion by macrophages, Cryptococcus neoformans can survive and replicate
intracellularly unless the macrophages become classically activated. The mechanism …

Mon1 is a guanine nucleotide exchange factor subunit that activates the Ypt7 Rab GTPase
and is essential for vacuole trafficking and autophagy in eukaryotic organisms. Here, we …

Pathogenic microorganisms employ specialized virulence factors to cause disease. Biofilm
formation and the production of a polysaccharide capsule are two important virulence factors …

The pathogenic fungus Cryptococcus neoformans delivers virulence factors such as capsule
polysaccharide to the cell surface to cause disease in vertebrate hosts. In this study, we …

The tea-oil tree Camellia oleifera is native to China and is cultivated in many parts of
southern China. This plant has been grown for over 2,000 years, mainly for its high-quality …

The airways of patients with cystic fibrosis (CF) are frequently colonized by various
filamentous fungi, mainly Aspergillus fumigatus and Scedosporium species. To establish …

Cryptococcus neoformans is a human fungal pathogen that often causes lung and brain
infections in immunocompromised patients, with a high fatality rate. Our previous results …

The current therapeutic challenges for treating fungal diseases demand new approaches
and new drugs. A promising strategy involves combination therapy with agents of distinct …