Introduction: Amyotrophic lateral sclerosis (ALS) is a progressive and incurable
neurodegenerative disorder that targets upper and lower motor neurons and leads to fatal …

Amyotrophic lateral sclerosis (ALS) is an adult-onset, lethal, paralytic disorder caused by the
degeneration of motor neurons. Our understanding of this disease has been greatly …

Objective Amyotrophic lateral sclerosis is an incurable disorder mainly characterized by
motoneuron degeneration. Mutations in the superoxide dismutase 1 (SOD 1) gene account …

Of familial amyotrophic lateral sclerosis (fALS) cases, 20% are caused by mutations in the
gene encoding human cytosolic Cu/Zn superoxide dismutase (hSOD1). Efficient translation …

Amyotrophic lateral sclerosis (ALS) is a fatal neurological disease caused by degeneration
of motor neurons leading to rapidly progressive paralysis. About 10% of cases are caused …

A myotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
the progressive degeneration of spinal motor neurons. Although mutations in dozens of …

Mutations in the superoxide dismutase gene (SOD1) are one cause of familial amyotrophic
lateral sclerosis [ALS; also known as motor neuron disease (MND)] in humans. ALS is a …

Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disorder
resulting from selective death of motor neurons in the brain and spinal cord. In≈ 25% of …

Amyotrophic lateral sclerosis (ALS) is a devastating neurologic disease that rapidly
progresses from mild motor symptoms to severe motor paralysis and premature death. Until …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease resulting in the
selective death of motor neurons in the brain and spinal cord. Some familial cases of ALS …