Understanding the role of neuropeptides in mediating emotional behaviors is an important
avenue for discovering novel drug targets for anxiety disorders. A role for galanin in …

The neuropeptide galanin coexists with norepinephrine and serotonin in neural systems
mediating emotion. Previous findings suggested that galanin modulates anxiety-related …

Neuropeptide galanin modulates a variety of central nervous system functions by signaling
through three G-protein-coupled receptor subtypes, GalR1 through GalR3. Galanin and its …

Galanin is a neuropeptide synthesized in many neuronal types including brainstem
norepinephrine-producing cells of the locus coeruleus and the serotonin-producing neurons …

Galanin (GAL) is a potential target for novel antidepressant or anti-anxiety drug
development. However, no integrated role for a “brain galanin system” in anxiety has yet …

Rationale Galanin and its receptors exert inhibitory neuromodulatory control over brain
monoamines. Rat studies revealed that galanin expression is upregulated by exposure to …

The neuropeptide galanin has been implicated in anxiety-related behaviors, cognition,
analgesia, and feeding in rodents. Neuromodulatory actions of galanin are mediated by …

The neuropeptide galanin (GAL) is widely distributed in the central and peripheral nervous
systems. It is a modulator of various physiological and pathological processes, and it …

Accumulating evidence indicates that disruption of galanin signaling is associated with
neuropsychiatric disease, but the precise functions of this neuropeptide remain largely …

The neuropeptide galanin is expressed in brain structures implicated in regulation of
emotionality. The amygdala is known to play a central role in mechanisms of fear and …