Determinants of alpha‐fetoprotein levels in patients with hepatocellular carcinoma: implications for its clinical use

EG Giannini, G Sammito, F Farinati, F Ciccarese… - Cancer, 2014 - Wiley Online Library
BACKGROUND α‐Fetoprotein (AFP) is a biomarker commonly used in the management of
patients with hepatocellular carcinoma (HCC), although the possible determinants of its …

Selective prognostic impact of serum α-fetoprotein level in patients with hepatocellular carcinoma: Analysis of 543 patients in a single center

TI Huo, YH Huang, WY Lui, JC Wu… - Oncology …, 2004 - spandidos-publications.com
The prognostic impact of serum α-fetoprotein (AFP) level in patients with hepatocellular
carcinoma (HCC) is controversial. This study aimed to investigate the predictive ability of …

[HTML][HTML] Value of α-fetoprotein in association with clinicopathological features of hepatocellular carcinoma

C Liu, GQ Xiao, LN Yan, B Li, L Jiang… - World journal of …, 2013 - ncbi.nlm.nih.gov
AIM: To explore the relationship between α-fetoprotein (AFP) and various clinicopathological
variables and different staging system of hepatocellular carcinoma (HCC) thoroughly …

Comprehensive clinicopathologic study of alpha fetoprotein‐expression in a large cohort of patients with hepatocellular carcinoma

DA Ridder, A Weinmann… - … journal of cancer, 2022 - Wiley Online Library
Alpha fetoprotein (AFP) is the most widely used diagnostic and prognostic serum biomarker
for hepatocellular carcinoma (HCC). Despite its wide clinical use, a systematic …

Using serum α-fetoprotein for prognostic prediction in patients with hepatocellular carcinoma: what is the most optimal cutoff?

CY Hsu, PH Liu, YH Lee, CY Hsia, YH Huang, HC Lin… - PloS one, 2015 - journals.plos.org
Background and Aims The prognostic ability of α-fetoprotein (AFP) for patients with
hepatocellular carcinoma (HCC) was examined by using different cutoff values. The optimal …

Decreasing trend of serum α-fetoprotein level in hepatocellular carcinoma

A Vipani, M Lauzon, M Luu, LR Roberts… - Clinical …, 2022 - cghjournal.org
Serum a-fetoprotein (AFP), a well-established biomarker for hepatocellular carcinoma
(HCC), increases the sensitivity of ultrasound-based surveillance programs for early stage …

The predictive ability of serum α‐fetoprotein for hepatocellular carcinoma is linked with the characteristics of the target population at surveillance

TI Huo, CY Hsia, CJ Chu, YH Huang… - Journal of surgical …, 2007 - Wiley Online Library
Background Serum α‐fetoprotein (AFP) is the most important tumor marker for
hepatocellular carcinoma (HCC). The reported predictive accuracy of AFP for HCC widely …

Level of α-fetoprotein predicts mortality among patients with hepatitis C–Related Hepatocellular Carcinoma

GL Tyson, Z Duan, JR Kramer, JA Davila… - Clinical …, 2011 - Elsevier
BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) can result from hepatitis C virus
(HCV)-related liver disease and is the fastest-growing cause of cancer-related death in the …

[HTML][HTML] Performance of serum α-fetoprotein levels in the diagnosis of hepatocellular carcinoma in patients with a hepatic mass

SL Chan, F Mo, PJ Johnson, DYW Siu, MHM Chan… - Hpb, 2014 - Elsevier
Objectives The role of serum α-fetoprotein (AFP) measurements in the diagnosis of
hepatocellular carcinoma (HCC) remains controversial. Some guidelines have advised …

Biology and significance of alpha‐fetoprotein in hepatocellular carcinoma

PR Galle, F Foerster, M Kudo, SL Chan… - Liver …, 2019 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the most common causes of cancer‐related
deaths globally due, in part, to the majority of patients being diagnosed with intermediate or …