The role of hepatitis B virus-specific memory CD8 T cells in the control of viral replication
Y Sobao, H Tomiyama, K Sugi, M Tokunaga, T Ueno… - Journal of …, 2002 - Elsevier
Background/Aims: The aim of this study is to clarify the differences of host immune
responses between acute self-limited and chronic persistent hepatitis B virus (HBV) …
responses between acute self-limited and chronic persistent hepatitis B virus (HBV) …
HBcAg-specific CD8 T cells play an important role in virus suppression, and acute flare-up is associated with the expansion of activated memory T cells
N Shimada, K Yamamoto, MJ Kuroda, R Terada… - Journal of clinical …, 2003 - Springer
We analyzed the prevalence and longitudinal fluctuation of hepatitis B virus (HBV)-specific
CD8 T cells in chronic HBV infection using an HLA-A2–HBc18-27 tetramer. Thirty-five HLA …
CD8 T cells in chronic HBV infection using an HLA-A2–HBc18-27 tetramer. Thirty-five HLA …
Kinetics of peripheral hepatitis B virus-specific CD8+ T cells in patients with onset of viral reactivation
J Aoki, Y Kowazaki, T Ohtsuki, R Okamoto… - Journal of …, 2013 - Springer
Background Patients with resolved hepatitis B virus (HBV) infection undergoing
chemotherapy or immunosuppressive therapy are potentially at risk of HBV reactivation …
chemotherapy or immunosuppressive therapy are potentially at risk of HBV reactivation …
Hepatitis B virus-specific CD4 T cell responses differentiate functional cure from chronic surface antigen+ infection
RC Hoogeveen, S Dijkstra, LM Bartsch… - Journal of …, 2022 - Elsevier
Background & Aims With or without antiviral treatment, few individuals achieve sustained
functional cure of chronic hepatitis B virus (HBV) infection. A better definition of what …
functional cure of chronic hepatitis B virus (HBV) infection. A better definition of what …
[HTML][HTML] The role of virus-specific CD8+ cells in liver damage and viral control during persistent hepatitis B virus infection
MK Maini, C Boni, CK Lee, JR Larrubia… - The Journal of …, 2000 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) is a noncytopathic virus, and the recognition of infected hepatocytes
by HBV-specific CD8 cells has been assumed to be the central mechanism causing both …
by HBV-specific CD8 cells has been assumed to be the central mechanism causing both …
Direct ex vivo analysis of hepatitis B virus-specific CD8+ T cells associated with the control of infection
Background & Aims: Cytotoxic T cells have been suggested to be responsible for lysis of
hepatitis B virus (HBV)-infected hepatocytes and control of virus infection. The frequency …
hepatitis B virus (HBV)-infected hepatocytes and control of virus infection. The frequency …
Hepatitis C viraemia reversibly maintains subset of antigen‐specific T‐bet+ tissue‐like memory B cells
LY Chang, Y Li, DE Kaplan - Journal of viral hepatitis, 2017 - Wiley Online Library
Background: Chronic antigen exposure and/or ageing increases the frequency of T‐box
expressed in T cells (T‐bet)‐expressing B‐lymphocytes in mice. The frequency and …
expressed in T cells (T‐bet)‐expressing B‐lymphocytes in mice. The frequency and …
Hepatitis B e-antigen persistency is associated with the properties of HBV-specific CD8 T cells in CHB patients
G Peng, B Luo, J Li, D Zhao, W Wu, F Chen… - Journal of Clinical …, 2011 - Springer
To investigate the correlation between the HBeAg and the properties of HBV-specific CD8 T
cells, as well as liver injury, serum HBV markers, liver histology, the frequency and …
cells, as well as liver injury, serum HBV markers, liver histology, the frequency and …
Decades after recovery from hepatitis B and HBsAg clearance the CD8+ T cell response against HBV core is nearly undetectable
H Kefalakes, C Jochum, G Hilgard, A Kahraman… - Journal of …, 2015 - Elsevier
Background & Aims CD8+ T cells are an essential component of a successful immune
response against hepatitis B virus (HBV). Patients who spontaneously clear HBsAg after …
response against hepatitis B virus (HBV). Patients who spontaneously clear HBsAg after …
Ex vivo Detection and Characterization of Hepatitis B Virus-Specific CD8+ T Cells in Patients Considered Immune Tolerant
In this study, we aimed to detect and characterize ex vivo virus-specific CD8+ T cells in
patients with immune-tolerant hepatitis B virus (HBV) infection. We investigated a Korean …
patients with immune-tolerant hepatitis B virus (HBV) infection. We investigated a Korean …