Background/Aims: The aim of this study is to clarify the differences of host immune
responses between acute self-limited and chronic persistent hepatitis B virus (HBV) …

We analyzed the prevalence and longitudinal fluctuation of hepatitis B virus (HBV)-specific
CD8 T cells in chronic HBV infection using an HLA-A2–HBc18-27 tetramer. Thirty-five HLA …

Background Patients with resolved hepatitis B virus (HBV) infection undergoing
chemotherapy or immunosuppressive therapy are potentially at risk of HBV reactivation …

Background & Aims With or without antiviral treatment, few individuals achieve sustained
functional cure of chronic hepatitis B virus (HBV) infection. A better definition of what …

Hepatitis B virus (HBV) is a noncytopathic virus, and the recognition of infected hepatocytes
by HBV-specific CD8 cells has been assumed to be the central mechanism causing both …

Background & Aims: Cytotoxic T cells have been suggested to be responsible for lysis of
hepatitis B virus (HBV)-infected hepatocytes and control of virus infection. The frequency …

Background: Chronic antigen exposure and/or ageing increases the frequency of T‐box
expressed in T cells (T‐bet)‐expressing B‐lymphocytes in mice. The frequency and …

To investigate the correlation between the HBeAg and the properties of HBV-specific CD8 T
cells, as well as liver injury, serum HBV markers, liver histology, the frequency and …

Background & Aims CD8+ T cells are an essential component of a successful immune
response against hepatitis B virus (HBV). Patients who spontaneously clear HBsAg after …

In this study, we aimed to detect and characterize ex vivo virus-specific CD8+ T cells in
patients with immune-tolerant hepatitis B virus (HBV) infection. We investigated a Korean …