[HTML][HTML] Binding mode of SARS-CoV-2 fusion peptide to human cellular membrane
Infection of human cells by the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV2) relies on its binding to a specific receptor and subsequent fusion of the viral and host …
CoV2) relies on its binding to a specific receptor and subsequent fusion of the viral and host …
Binding of SARS-CoV-2 fusion peptide to host endosome and plasma membrane
During infection the SARS-CoV-2 virus fuses its viral envelope with cellular membranes of
its human host. The viral spike (S) protein mediates both the initial contact with the host cell …
its human host. The viral spike (S) protein mediates both the initial contact with the host cell …
[HTML][HTML] Ca2+-dependent mechanism of membrane insertion and destabilization by the SARS-CoV-2 fusion peptide
G Khelashvili, A Plante, M Doktorova, H Weinstein - Biophysical Journal, 2021 - cell.com
Cell penetration after recognition of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) virus by the ACE2 receptor and the fusion of its viral envelope membrane …
(SARS-CoV-2) virus by the ACE2 receptor and the fusion of its viral envelope membrane …
Computational insight into the mechanism of SARS-CoV-2 membrane fusion
S Borkotoky, D Dey, M Banerjee - Journal of Chemical Information …, 2021 - ACS Publications
Membrane fusion, a key step in the early stages of virus propagation, allows the release of
the viral genome in the host cell cytoplasm. The process is initiated by fusion peptides that …
the viral genome in the host cell cytoplasm. The process is initiated by fusion peptides that …
Host cell membrane capture by the SARS-CoV-2 spike protein fusion intermediate
R Su, J Zeng, TC Marcink, M Porotto… - ACS Central …, 2023 - ACS Publications
Cell entry by SARS-CoV-2 is accomplished by the S2 subunit of the spike S protein on the
virion surface by capture of the host cell membrane and fusion with the viral envelope …
virion surface by capture of the host cell membrane and fusion with the viral envelope …
Exploring the pH dependence of the SARS‐CoV‐2 complete fusion domain and the role of its unique structural features
D Birtles, AE Oh, J Lee - Protein Science, 2022 - Wiley Online Library
SARS‐CoV‐2 may enter target cells through the process of membrane fusion at either the
plasma (~ pH 7.4–7.0) or endosomal (~ pH 6.5–5.0) membrane in order to deliver its genetic …
plasma (~ pH 7.4–7.0) or endosomal (~ pH 6.5–5.0) membrane in order to deliver its genetic …
[HTML][HTML] Negatively charged residues in the membrane ordering activity of SARS-CoV-1 and-2 fusion peptides
AL Lai, JH Freed - Biophysical Journal, 2022 - cell.com
Entry of coronaviruses into host cells is mediated by the viral spike protein. Previously, we
identified the bona fide fusion peptides (FPs) for severe acute respiratory syndrome …
identified the bona fide fusion peptides (FPs) for severe acute respiratory syndrome …
[HTML][HTML] SARS-CoV fusion peptides induce membrane surface ordering and curvature
Viral membrane fusion is an orchestrated process triggered by membrane-anchored viral
fusion glycoproteins. The S2 subunit of the spike glycoprotein from severe acute respiratory …
fusion glycoproteins. The S2 subunit of the spike glycoprotein from severe acute respiratory …
Identifying distinct structural features of the SARS-CoV-2 spike protein fusion domain essential for membrane interaction
D Birtles, J Lee - Biochemistry, 2021 - ACS Publications
The SARS-CoV-2 spike protein is the primary antigenic determinant of the virus and has
been studied extensively, yet the process of membrane fusion remains poorly understood …
been studied extensively, yet the process of membrane fusion remains poorly understood …
Interaction of a peptide from the pre-transmembrane domain of the severe acute respiratory syndrome coronavirus spike protein with phospholipid membranes
J Guillen, MR Moreno, AJ Perez-Berna… - The journal of …, 2007 - ACS Publications
The severe acute respiratory syndrome coronavirus (SARS-CoV) envelope spike (S)
glycoprotein, a Class I viral fusion protein, is responsible for the fusion between the …
glycoprotein, a Class I viral fusion protein, is responsible for the fusion between the …