NADH: the redox sensor in aging-related disorders.

G Schiuma, D Lara, J Clement, M Narducci… - … and Redox Signaling, 2024 - liebertpub.com
Significance: NADH represents the reduced form of NAD+, and together they constitute the
two forms of the Nicotinamide adenine dinucleotide whose balance is named as the …

Cytoplasmic and mitochondrial NADPH-coupled redox systems in the regulation of aging

PC Bradshaw - Nutrients, 2019 - mdpi.com
The reduced form of nicotinamide adenine dinucleotide phosphate (NADPH) protects
against redox stress by providing reducing equivalents to antioxidants such as glutathione …

NAD and the aging process: Role in life, death and everything in between

CCS Chini, MG Tarragó, EN Chini - Molecular and cellular endocrinology, 2017 - Elsevier
Life as we know it cannot exist without the nucleotide nicotinamide adenine dinucleotide
(NAD). From the simplest organism, such as bacteria, to the most complex multicellular …

NAD+ metabolism and its roles in cellular processes during ageing

AJ Covarrubias, R Perrone, A Grozio… - Nature reviews Molecular …, 2021 - nature.com
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme for redox reactions, making it
central to energy metabolism. NAD+ is also an essential cofactor for non-redox NAD+ …

The central role of the NAD+ molecule in the development of aging and the prevention of chronic age-related diseases: strategies for NAD+ modulation

B Poljšak, V Kovač, S Špalj, I Milisav - International journal of molecular …, 2023 - mdpi.com
The molecule NAD+ is a coenzyme for enzymes catalyzing cellular redox reactions in
several metabolic pathways, encompassing glycolysis, TCA cycle, and oxidative …

[HTML][HTML] Therapeutic potential of boosting NAD+ in aging and age-related diseases

Y Aman, Y Qiu, J Tao, EF Fang - Translational Medicine of Aging, 2018 - Elsevier
Nicotinamide adenine dinucleotide (NAD+) is an essential cofactor in all living cells that is
involved in fundamental biological processes. NAD+ depletion has been associated with …

[HTML][HTML] Role of NAD+ in regulating cellular and metabolic signaling pathways

S Amjad, S Nisar, AA Bhat, MP Frenneaux, K Fakhro… - Molecular …, 2021 - Elsevier
Background Nicotinamide adenine dinucleotide (NAD+), a critical coenzyme present in
every living cell, is involved in a myriad of metabolic processes associated with cellular …

[HTML][HTML] The balance between NAD+ biosynthesis and consumption in ageing

Ø Strømland, J Diab, E Ferrario, LJ Sverkeli… - Mechanisms of Ageing …, 2021 - Elsevier
Nicotinamide adenine dinucleotide (NAD+) is a vital coenzyme in redox reactions. NAD+ is
also important in cellular signalling as it is consumed by PARPs, SARM1, sirtuins and CD38 …

NAD (H) and NADP (H) redox couples and cellular energy metabolism

W Xiao, RS Wang, DE Handy… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: The nicotinamide adenine dinucleotide (NAD+)/reduced NAD+ (NADH) and
NADP+/reduced NADP+ (NADPH) redox couples are essential for maintaining cellular …

Two different methods of quantification of oxidized nicotinamide adenine dinucleotide (NAD+) and reduced nicotinamide adenine dinucleotide (NADH) intracellular …

KS Kanamori, GC de Oliveira, M Auxiliadora-Martins… - Bio …, 2018 - bio-protocol.org
Current studies on the age-related development of metabolic dysfunction and frailty are
each day in more evidence. It is known, as aging progresses, nicotinamide adenine …