An update of research animal models of inflammatory bowel disease

Z Baydi, Y Limami, L Khalki, N Zaid… - The Scientific World …, 2021 - Wiley Online Library
Inflammatory bowel disease (IBD) is a group of chronic disorders that includes two main
disease forms, Crohn's disease, and ulcerative colitis. The understanding of the intestinal …

Mouse models of inflammatory bowel disease

S Wirtz, MF Neurath - Advanced drug delivery reviews, 2007 - Elsevier
Animal models of intestinal inflammation are indispensable for our understanding of the
pathogenesis of Crohn disease and Ulcerative colitis, the idiopathic forms of inflammatory …

Mouse models of inflammatory bowel disease for investigating mucosal immunity in the intestine

G Bamias, KO Arseneau… - Current Opinion in …, 2017 - journals.lww.com
Animal models of intestinal inflammation continue to be important research tools with high
significance for understanding the pathogenesis of IBD and exploring novel therapeutic …

Animal models of inflammatory bowel disease

A Mizoguchi - Progress in molecular biology and translational …, 2012 - Elsevier
Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory condition that is
medicated by genetic, immune, and environmental factors. At least 66 different kinds of …

Immunopathological characterization of selected mouse models of inflammatory bowel disease: comparison to human disease

YL Jones-Hall, MB Grisham - Pathophysiology, 2014 - Elsevier
Inflammatory bowel diseases (IBD) are chronic, relapsing conditions of multifactorial
etiology. The two primary diseases of IBD are Crohn's disease (CD) and ulcerative colitis …

Animal models of inflammatory bowel disease: an overview

JC Hoffmann, NN Pawlowski, AA Kühl, W Höhne… - Pathobiology, 2003 - karger.com
Inflammatory bowel disease (IBD) research has been performed in human in vitro studies
and in in vivo studies using appropriate animal models. Such animal models allow both the …

Animal models of inflammatory bowel diseases: illuminating the pathogenesis of colitis, ileitis and cancer

MF Neurath - Digestive Diseases, 2012 - karger.com
Background/Aims: Inflammatory bowel diseases (IBD) are chronic relapsing diseases of
unknown origin. In spite of improved options for therapy, many patients with IBD have an …

[HTML][HTML] Experimental models of inflammatory bowel diseases

P Kiesler, IJ Fuss, W Strober - Cellular and molecular gastroenterology and …, 2015 - Elsevier
The understanding of the intestinal inflammation occurring in the inflammatory bowel
diseases (IBD) has been immeasurably advanced by the development of the now numerous …

[HTML][HTML] Uncovering pathogenic mechanisms of inflammatory bowel disease using mouse models of Crohn's disease–like ileitis: what is the right model?

F Cominelli, KO Arseneau… - Cellular and molecular …, 2017 - Elsevier
Crohn's disease and ulcerative colitis, together known as inflammatory bowel disease, are
debilitating chronic disorders of unknown cause and cure. Our evolving understanding of …

Murine Models of Inflammatory Bowel Disease (IBD) Challenges of Modeling Human Disease

J DeVoss, L Diehl - Toxicologic pathology, 2014 - journals.sagepub.com
Animal models of human disease are a critical tool in both basic research and drug
development. The results of preclinical efficacy studies often inform progression of …