Transcriptional response of Aspergillus fumigatus to copper and the role of the Cu chaperones
D Anabosi, Z Meir, Y Shadkchan, M Handelman… - Virulence, 2021 - Taylor & Francis
Aspergillus fumigatus is the leading cause of life-threatening invasive mold infections in
immunocompromised individuals. This ubiquitous saprophyte possesses several natural …
immunocompromised individuals. This ubiquitous saprophyte possesses several natural …
[HTML][HTML] Copper homeostasis in Aspergillus fumigatus: opportunities for therapeutic development
J Song, R Li, J Jiang - Frontiers in microbiology, 2019 - frontiersin.org
Aspergillus fumigatus can cause severe invasive aspergillosis in immunocompromised
individuals. Copper, an essential but potentially toxic trace element for A. fumigatus, plays a …
individuals. Copper, an essential but potentially toxic trace element for A. fumigatus, plays a …
The Aspergillus fumigatus transcription factor AceA is involved not only in Cu but also in Zn detoxification through regulating transporters CrpA and ZrcA
Z Cai, W Du, Z Zhang, L Guan, Q Zeng… - Cellular …, 2018 - Wiley Online Library
Abstract Copper (Cu) and zinc (Zn) are essential nutrients for both pathogens and hosts;
however, their excess accumulation is toxic for all cells. The Aspergillus transcription factor …
however, their excess accumulation is toxic for all cells. The Aspergillus transcription factor …
Aspergillus fumigatus AcuM regulates both iron acquisition and gluconeogenesis
H Liu, FN Gravelat, LY Chiang, D Chen… - Molecular …, 2010 - Wiley Online Library
Relatively few transcription factors that govern the virulence of Aspergillus fumigatus are
known. We constructed 11 A. fumigatus transcription factor mutants and screened them for …
known. We constructed 11 A. fumigatus transcription factor mutants and screened them for …
Divergent Targets of Aspergillus fumigatus AcuK and AcuM Transcription Factors during Growth In Vitro versus Invasive Disease
ABSTRACT In Aspergillus nidulans, the AcuK and AcuM transcription factors form a complex
that regulates gluconeogenesis. In Aspergillus fumigatus, AcuM governs gluconeogenesis …
that regulates gluconeogenesis. In Aspergillus fumigatus, AcuM governs gluconeogenesis …
A novel Zn2-Cys6 transcription factor clcA contributes to copper homeostasis in Aspergillus fumigatus
Y Kusuya, C Bian, D Hagiwara, S Ban, H Takahashi - Current Genetics, 2022 - Springer
The filamentous fungus Aspergillus fumigatus is the most important pathogenic fungus
among Aspergillus species associated with aspergillosis. A. fumigatus is exposed to diverse …
among Aspergillus species associated with aspergillosis. A. fumigatus is exposed to diverse …
Copper Utilization, Regulation, and Acquisition by Aspergillus fumigatus
Copper is an essential micronutrient for the opportunistic human pathogen, Aspergillus
fumigatus. Maintaining copper homeostasis is critical for survival and pathogenesis. Copper …
fumigatus. Maintaining copper homeostasis is critical for survival and pathogenesis. Copper …
Contribution of ATPase copper transporters in animal but not plant virulence of the crossover pathogen Aspergillus flavus
The ubiquitous fungus Aspergillus flavus is notorious for contaminating many important
crops and food-stuffs with the carcinogenic mycotoxin, aflatoxin. This fungus is also the …
crops and food-stuffs with the carcinogenic mycotoxin, aflatoxin. This fungus is also the …
The Role of Zinc in Copper Homeostasis of Aspergillus fumigatus
S Kang, H Seo, HS Moon, JH Kwon, YS Park… - International journal of …, 2020 - mdpi.com
Copper is an essential metal ion that performs many physiological functions in living
organisms. Deletion of Afmac1, which is a copper-responsive transcriptional activator in A …
organisms. Deletion of Afmac1, which is a copper-responsive transcriptional activator in A …
Absent regulation of iron acquisition by the copper regulator Mac1 in A. fumigatus
A Yap, M Misslinger, H Haas - Biochemical Journal, 2020 - portlandpress.com
Aspergillus fumigatus is the most common cause of invasive aspergillosis, a life-threatening
infection mainly affecting immunocompromised patients. The essential metals copper and …
infection mainly affecting immunocompromised patients. The essential metals copper and …