Development of an enzyme-linked immunosorbent assay for the quantification of amiodarone

T Saita, H Fujito, M Mori - Biological and Pharmaceutical Bulletin, 2002 - jstage.jst.go.jp
MATERIALS AND METHODS Equipment The IR spectrum was recorded using a Hitachi 270-
30 spectrometer (Tokyo, Japan). A proton nuclear magnetic resonance (1H-NMR) spectrum …

Rapid liquid chromatographic assay for the determination of amiodarone and its N‐deethyl metabolite in plasma, urine, and bile

SJ Weir, CT Ueda - Journal of pharmaceutical sciences, 1985 - Wiley Online Library
A rapid high‐performance liquid chromatographic assay was developed for the
determination of amiodarone (1) and its N‐deethyl metabolite (desethylamiodarone, 2) in …

Simultaneous determination of amiodarone and its metabolite desethylamiodarone by high-performance liquid chromatography with chemiluminescent detection

T Pérez-Ruiz, C Martínez-Lozano… - Analytica chimica …, 2008 - Elsevier
A novel method was developed for the determination of amiodarone and
desethylamiodarone by high-performance liquid chromatography (HPLC) coupled with …

High-performance liquid chromatographic assay for amiodarone N-deethylation activity in human liver microsomes using solid-phase extraction

N Hanioka, Y Saito, A Soyama, M Ando… - … of Chromatography B, 2002 - Elsevier
A selective and sensitive assay for amiodarone N-deethylation activity in human liver
microsomes by high-performance liquid chromatography (HPLC) with UV detection is …

Simultaneous determination of amiodarone and its major metabolite desethylamiodarone in plasma, urine and tissues by high-performance liquid chromatography

TA Plomp, M Engels, EOR De Medina… - … of Chromatography B …, 1983 - Elsevier
A simple and sensitive high-performance liquid chromatographic method for the
simultaneous assay of amiodarone and desethylarniodarone in plasma, urine and tissues …

Validation of a Stability‐Indicating HPLC Method for the Determination of Amiodarone HCl and Its Related Substances in Amiodarone HCl Injection

MJ Christopherson, KJ Yoder… - Journal of liquid …, 2004 - Taylor & Francis
The validation of a gradient high performance liquid chromatographic (HPLC) procedure
employing ultraviolet (UV) detection for the analysis of amiodarone HCl and two of its related …

[PDF][PDF] High-performance liquid chromatographic assay of amiodarone in rat plasma

AS Jun, DR Brocks - J Pharm Pharmaceut Sci, 2001 - sites.ualberta.ca
Purpose. A high-performance liquid chromatographic method is described for the
determination of amiodarone in rat plasma. Methods. After liquid-liquid extraction, the …

High-performance liquid chromatographic assay for amiodarone N-deethylation in microsomes of rat liver

JM Trivier, J Pommery, C Libersa, J Caron… - … of Chromatography B …, 1992 - Elsevier
A reversed-phase high-performance liquid chromatographic assay using ultraviolet
detection is described for determining the production of the major N-dealkylated metabolite …

Clinical measurement of serum amiodarone and desethylamiodarone by using solid-phase extraction followed by HPLC with a high-carbon reversed-phase column

MA Jandreski, WE Vanderslice - Clinical chemistry, 1993 - academic.oup.com
We describe a rapid, simple HPLC method routinely used in our clinical laboratory for
determining amiodarone and its metabolite desethylamiodarone. These compounds are …

A rapid HPLC method for the simultaneous determination of amiodarone and its major metabolite in rat plasma and tissues: a useful tool for pharmacokinetic studies

M Rodrigues, G Alves, A Ferreira… - Journal of …, 2013 - academic.oup.com
A rapid and sensitive high-performance liquid chromatography (HPLC) method was
developed and validated in rat plasma and tissue (heart, liver, kidney and lung) …