[HTML][HTML] Effect of lifestyle intervention on the risk of incident diabetes in individuals with impaired fasting glucose and low or high genetic risk for the development of …

U Schwab, M Lankinen, M Laakso - Food & Nutrition Research, 2021 - ncbi.nlm.nih.gov
Purpose Genetic and lifestyle/environmental factors as well as their interplay contribute to
the pathogenesis of type 2 diabetes (T2D). Several trials have shown that lifestyle …

Effects of genetic risk on incident type 2 diabetes and glycemia: the T2D-GENE lifestyle intervention trial

MA Lankinen, P Nuotio, S Kauppinen… - The Journal of …, 2024 - academic.oup.com
Context Lifestyle intervention prevents or delays type 2 diabetes (T2D) in subjects at a high
risk of T2D. However, it is not known whether genetic variants modify the effect on incident …

Changing the odds. What do we learn from prevention studies targeted at people with a positive family history of type 2 diabetes?

WH Heideman, BJC Middelkoop, V Nierkens… - Primary Care …, 2011 - Elsevier
People with a positive family history of type 2 diabetes (T2DM) are at high risk of developing
diabetes. We set out to review the literature reporting on the development and/or evaluation …

The complex interplay of genetic and lifestyle risk factors in type 2 diabetes: an overview

PW Franks - Scientifica, 2012 - Wiley Online Library
Type 2 diabetes (T2D) is one of the scourges of modern times, with many millions of people
affected by the disease. Diabetes occurs most frequently in those who are overweight or …

Type 2 diabetes: unravelling the interaction between genetic predisposition and lifestyle

W Rathmann, B Kowall, G Giani - Diabetologia, 2011 - Springer
The high concordance rate of type 2 diabetes in monozygotic twins, the increased risk of
diabetes in the offspring of affected parents and the difference in the prevalence of diabetes …

Susceptibility to type 2 diabetes mellitus—from genes to prevention

MF Hivert, JL Vassy, JB Meigs - Nature Reviews Endocrinology, 2014 - nature.com
Abstract Knowledge of the genetics of type 2 diabetes mellitus (T2DM) has evolved
tremendously over the past few years. Following advances in technology and analytical …

Genetic risk of type 2 diabetes modifies the effects of a lifestyle intervention aimed at the prevention of gestational and postpartum diabetes

E Huvinen, J Lahti, MM Klemetti, PH Bergman… - Diabetologia, 2022 - Springer
Aims/hypothesis The aim of this study was to assess the interaction between genetic risk
and lifestyle intervention on the occurrence of gestational diabetes mellitus (GDM) and …

The EPIC-InterAct study: a study of the interplay between genetic and lifestyle behavioral factors on the risk of type 2 diabetes in European populations

NG Forouhi, NJ Wareham - Current nutrition reports, 2014 - Springer
The rising prevalence of type 2 diabetes around the world and the global pattern of variation
in risk between countries have been widely attributed to an interplay between rising rates of …

Lifestyle modifies the diabetes-related metabolic risk, conditional on individual genetic differences

J Shin, X Zhou, JTM Tan, E Hyppönen… - Frontiers in …, 2022 - frontiersin.org
Metabolic syndrome is a group of heritable metabolic traits that are highly associated with
type 2 diabetes (T2DM). Classical interventions to T2DM include individual self …

Gene‐lifestyle interaction on risk of type 2 diabetes: A systematic review

S Dietrich, S Jacobs, JS Zheng, K Meidtner… - Obesity …, 2019 - Wiley Online Library
The pathophysiological influence of gene‐lifestyle interactions on the risk to develop type 2
diabetes (T2D) is currently under intensive research. This systematic review summarizes the …