In vitro Imaging and Characterization of Hematopoietic Stem Cells on E/P Selectin Surfaces

A Rakhmatulina - 2023 - repository.kaust.edu.sa
Understanding hematopoietic stem cells is essential for the treatment of blood-borne
illnesses. For marrow reconstitution, the number of accessible HSC donors is frequently …

Spatial confinement and temporal dynamics of selectin ligands enable stable hematopoietic stem cell rolling

B Al Alwan, K AbuZineh, S Nozue… - Available at SSRN …, 2020 - papers.ssrn.com
Hematopoietic stem/progenitor cell (HSPC) homing is initiated by tethering and rolling of the
cells on endothelium through selectin-ligand interactions. Although multiple factors that …

[HTML][HTML] Single-molecule imaging and microfluidic platform reveal molecular mechanisms of leukemic cell rolling

B Al Alwan, K AbuZineh, S Nozue… - Communications …, 2021 - nature.com
Hematopoietic stem/progenitor cell (HSPC) and leukemic cell homing is an important
biological phenomenon that occurs through key interactions between adhesion molecules …

Microfluidics-based super-resolution microscopy enables nanoscopic characterization of blood stem cell rolling

K AbuZineh, LI Joudeh, B Al Alwan, SM Hamdan… - Science …, 2018 - science.org
Hematopoietic stem/progenitor cell (HSPC) homing occurs via cell adhesion mediated by
spatiotemporally organized ligand-receptor interactions. Although molecules and biological …

Nanoscopic characterization of cell migration under flow using optical and electron microscopy

A Alghamdi, A Tamra, A Rakhmatulina… - Analytical …, 2023 - ACS Publications
Hematopoietic stem/progenitor cell (HSPC) and leukemic cell homing is an important
biological phenomenon that takes place through essential interactions with adhesion …

Quantitative characterization of E-selectin interaction with native CD44 and PSGL-1 using a real-time immunoprecipitation-based binding assay

DBK Abu Samra, A Al Kilani, S Hamdan, K Sakashita… - 2015 - repository.kaust.edu.sa
Selectins (E-, P-, and L-selectins) interact with glycoprotein ligands to mediate the essential
tethering/rolling step in cell transport and delivery that captures migrating cells from the …

Relationship between selectin-mediated rolling of hematopoietic stem and progenitor cells and progression in hematopoietic development

AW Greenberg, WG Kerr… - Blood, The Journal of the …, 2000 - ashpublications.org
Current understanding of the adhesion molecules and mechanisms regulating
hematopoietic stem and progenitor cell (HSPC) homing to the bone marrow is limited. In …

[HTML][HTML] Quantitative characterization of E-selectin interaction with native CD44 and P-selectin glycoprotein ligand-1 (PSGL-1) using a real time immunoprecipitation …

DB AbuSamra, A Al-Kilani, SM Hamdan… - Journal of Biological …, 2015 - ASBMB
Selectins (E-, P-, and L-selectins) interact with glycoprotein ligands to mediate the essential
tethering/rolling step in cell transport and delivery that captures migrating cells from the …

[HTML][HTML] Stem cell enrichment with selectin receptors: mimicking the pH environment of trauma

TM Cao, MJ Mitchell, J Liesveld, MR King - Sensors, 2013 - mdpi.com
The isolation of hematopoietic stem and progenitor cells (HSPCs) is critical for
transplantation therapy and HSPC research, however current isolation techniques can be …

[HTML][HTML] Overlapping roles for endothelial selectins in murine hematopoietic stem/progenitor cell homing to bone marrow

LK Nabors, LD Wang, AJ Wagers, GS Kansas - Experimental hematology, 2013 - Elsevier
Selectins are carbohydrate-binding adhesion molecules that are critically involved in
leukocyte recognition of endothelium. The endothelial selectins have been implicated in …