Abstract Model substrates presenting biochemical cues immobilized in a controlled and well-
defined manner are of great interest for their applications in biointerface studies that …

Background Granulocyte colony-stimulating factor (G-CSF)-mediated mobilization of
hematopoietic stem cells (HSCs) is a well-established method to prepare HSCs for …

Rolling adhesion is the behaviour that leukocytes and circulating tumour cells exhibit as they
passively roll along blood vessel walls under flow. It plays a critical role in capturing cells in …

E-selectin-mediated leukocyte adhesion on endothelial cells is a critical event in the
inflammatory response. Site density determination of E-selectin on the substrate surface is …

Dynamic cell–microenvironment interactions regulate many biological events and play a
critical role in tissue regeneration. Cell homing to targeted tissues requires well balanced …

Interactions of selectins with cell-surface glycoconjugates mediate tethering and rolling
adhesion of leukocytes and platelets on vascular surfaces. Recent studies have helped …

Hematopoietic stem and progenitor cells (HSPC) express at their surface an array of cell
adhesion receptors that enables them to interact with extracellular matrix components and …

Cells of the hematopoietic system undergo rapid turnover. Each day, humans require the
production of about one hundred billion new blood cells for proper function. Hematopoietic …

The cell surface glycoprotein CD34 is widely recognized as a marker of hematopoietic
stem/progenitor cells (HSPCs), but its physiological role on HSPCs remains elusive …

We have previously identified a novel function for the adhesion molecule E-selectin–
awakening otherwise dormant hematopoietic stem cells (HSC) and inducing lineage …