Analysis of physiologic E-selectin-mediated leukocyte rolling on microvascular endothelium

G Wiese, SR Barthel, CJ Dimitroff - JoVE (Journal of Visualized …, 2009 - jove.com
E-selectin is a type-1 membrane protein on microvascular endothelial cells that helps initiate
recruitment of circulating leukocytes to cutaneous, bone and inflamed tissues. E-selectin …

Steering trajectories of rolling cells by 2D asymmetric receptor patterning

CH Lee, S Bose, JM Karp… - Proceedings of the 2010 …, 2010 - ieeexplore.ieee.org
We demonstrate a simple method to make high-resolution P-selectin patterns based on
microcontact printing for controlling cell rolling. SEM characterization revealed well-defined …

Cell surface engineering of mesenchymal stem cells

D Sarkar, W Zhao, A Gupta, WL Loh, R Karnik… - Mesenchymal Stem Cell …, 2011 - Springer
By leveraging the capacity to promote regeneration, stem cell therapies offer enormous
hope for solving some of the most tragic illnesses, diseases, and tissue defects world-wide …

Studying cell rolling trajectories on asymmetric receptor patterns

CH Lee, S Bose, KJ Van Vliet, JM Karp… - JoVE (Journal of …, 2011 - jove.com
Lateral displacement of cells orthogonal to a flow stream by rolling on asymmetric receptor
patterns presents an opportunity for development of new devices for label-free separation …

[HTML][HTML] Functional ramifications for the loss of P-selectin expression on hematopoietic and leukemic stem cells

C Sullivan, Y Chen, Y Shan, Y Hu, C Peng, H Zhang… - PLoS …, 2011 - journals.plos.org
Hematopoiesis is a tightly regulated biological process that relies upon complicated
interactions between blood cells and their microenvironment to preserve the homeostatic …

Prolonged transendothelial migration of human haematopoietic stem and progenitor cells (HSPCs) towards hydrogel-released SDF1

L Sobkow, FP Seib, L Prodanov, I Kurth, J Drichel… - Annals of …, 2011 - Springer
The therapeutic success of haematopoetic stem and progenitor cell (HSPC) transplantation
is critically dependent on HSPC engraftment in the bone marrow. Gradients of stromal cell …

Photoconversion and chromatographic microfluidic system reveals differential cellular phenotypes of adhesion velocity versus persistence in shear flow

KG Birmingham, IE Robinson, EE Edwards… - Lab on a Chip, 2020 - pubs.rsc.org
An integrated photoconversion and cell sorting parallel-plate chromatography channel
enabling the measurement of instantaneous and average velocities of cells mediating …

[HTML][HTML] Intravital microscopy identifies selectins that regulate T cell traffic into allografts

TR Jones, N Shirasugi, AB Adams… - The Journal of …, 2003 - Am Soc Clin Investig
T cell homing to sites of injury and inflammation is a critical step for adaptive immune
responses. While much has been learned regarding T cell homing to lymphoid tissues, few …

Molecular and Cellular Contributions to Selectin‐Dependent Leukocyte Adhesion Under Flow

RP McEver - Leukocyte Trafficking: Molecular Mechanisms …, 2005 - books.google.com
The selectins are type I membrane glycoproteins that mediate rolling adhesion of leukocytes
and platelets on vascular surfaces under flow [1, 2]. L-selectin is expressed on most …

[HTML][HTML] Low force decelerates L-selectin dissociation from P-selectin glycoprotein ligand-1 and endoglycan

KK Sarangapani, T Yago, AG Klopocki… - Journal of biological …, 2004 - ASBMB
Selectin-ligand interactions mediate the tethering and rolling of circulating leukocytes on
vascular surfaces during inflammation and immune surveillance. To support rolling, these …