Real‐world tyrosine kinase inhibitor treatment pathways, monitoring patterns and responses in patients with chronic myeloid leukaemia in the United Kingdom: the UK …

D Milojkovic, NCP Cross, S Ali, J Byrne… - British journal of …, 2021 - Wiley Online Library
Management of chronic myeloid leukaemia (CML) has recently undergone dramatic
changes, prompting the European LeukemiaNet (ELN) to issue recommendations in 2013; …

Real-world therapeutic response and tyrosine kinase inhibitor discontinuation in chronic phase-chronic myeloid leukemia: data from the French observatory

S Saugues, C Lambert, E Daguenet, HJ Ansah… - Annals of …, 2022 - Springer
Guidelines for tyrosine kinase inhibitor (TKI)-treated chronic phase-chronic myeloid
leukemia (CML) management are essentially based on data from clinical research trials; …

Early switch in tyrosine kinase inhibitor therapy for patients with chronic myeloid leukemia: An emerging clinical question

K Sweet, J Pinilla-Ibarz - Critical Reviews in Oncology/Hematology, 2016 - Elsevier
Response to frontline BCR-ABL1-targeted tyrosine kinase inhibitor (TKI) therapy is
associated with an improved prognosis for patients with chronic myeloid leukemia (CML) …

Critical appraisal of European LeukemiaNet (ELN) 2013 recommendations for the management of chronic myeloid leukemia: is it early for a warning?

AE Eskazan, MC Ar, T Soysal - Expert Review of Hematology, 2016 - Taylor & Francis
Management of chronic myeloid leukemia (CML) has undergone a rapid evolution with the
invention of imatinib–the first tyrosine kinase inhibitor (TKI) approved for the treatment of …

Impact of ELN recommendations in the management of first‐line treated chronic myeloid leukaemia patients: a French cross‐sectional study

G Etienne, F Huguet, A Guerci‐Bresler… - British journal of …, 2016 - Wiley Online Library
The availability of tyrosine kinase inhibitors has extended therapeutic options for chronic
myeloid leukaemia (CML) patients. Monitoring recommendations and clinical response …

Adverse outcomes in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: follow‐up of patients diagnosed 2002–2017 in a complete coverage …

T Dahlén, G Edgren, P Ljungman… - American Journal of …, 2022 - Wiley Online Library
Tyrosine kinase inhibitors (TKIs) have profoundly improved the clinical outcome for patients
with chronic myeloid leukemia (CML), but their overall survival is still subnormal and the …

[HTML][HTML] Treatment outcome in a population-based,'real-world'cohort of patients with chronic myeloid leukemia

IGP Geelen, N Thielen, JJWM Janssen… - …, 2017 - ncbi.nlm.nih.gov
Evaluations of the 'real-world'efficacy and safety of tyrosine kinase inhibitors in patients with
chronic myeloid leukemia are scarce. A nationwide, population-based, chronic myeloid …

[HTML][HTML] Improving outcomes in chronic myeloid leukemia over time in the era of tyrosine kinase inhibitors

P Chopade, LP Akard - Clinical Lymphoma Myeloma and Leukemia, 2018 - Elsevier
Most patients with chronic myeloid leukemia (CML) receiving treatment with BCR-ABL1
tyrosine kinase inhibitors (TKIs) will achieve favorable responses. Moreover, TKI therapy …

Analysis of 2013 European LeukaemiaNet (ELN) responses in chronic phase CML across four frontline TKI modalities and impact on clinical outcomes

P Jain, H Kantarjian, K Sasaki… - British journal of …, 2016 - Wiley Online Library
This study assessed the relevance of 2013 European LeukaemiaNet (ELN) response
categories on patients treated with common frontline tyrosine kinase inhibitors (TKI) in …

A multicenter retrospective chart review study of treatment and disease patterns and clinical outcomes of patients with chronic-phase chronic myeloid leukemia in third …

FE Nicolini, F Huguet, L Huynh, C Xu, C Bouvier… - Cancers, 2023 - mdpi.com
Simple Summary Many patients with chronic-phase chronic myeloid leukemia (CP-CML)
treated with a tyrosine kinase inhibitor (TKI) experience disease progression and switch to …