Significance: Currently 10%–15% of couples in reproductive age face infertility issues. More
importantly, male factor contributes to 50% of these cases (either alone or in combination …

During the last decade, several studies have shown that mitochondrial parameters, such as
integrity, respiratory activity, membrane potential and ROS production are intimately linked …

Simple Summary Mitochondria play a crucial role in numerous cellular processes, including
energy production, apoptosis, and calcium homeostasis. In the male reproductive system …

Besides adenine triphosphate (ATP) production for sustaining motility, the mitochondria of
sperm also host other critical cellular functions during germ cell development and …

While critical for male fertility preservation, cryopreservation damage reduces sperm quality
and fertilization potential. This study investigated whether the addition of mitochondrial …

Although mitochondria are best known for being the eukaryotic cell powerhouses, these
organelles participate in various cellular functions besides ATP production, such as calcium …

Mitochondria are vital organelles with a multifaceted role in cellular bioenergetics,
biosynthesis, signaling and calcium homeostasis. During oxidative phosphorylation, sperm …

The diagnosis of male infertility is based essentially on the patient's medical history and a
standard semen analysis. However, the latter rarely provides information on the causes of a …

Mitochondria are structurally and functionally unique organelles in male gametes.
Apparently, as the only organelles remaining in mature sperm, mitochondria not only …

Mitochondria are structurally and functionally distinct organelles that produce adenosine
triphosphate (ATP) through oxidative phosphorylation (OXPHOS), to provide energy to …