Purpose: Prolonged pneumoperitoneum, as required for laparoscopic nephrectomy,
decreases renal blood flow (RBF). We hypothesized that intravascular isotonic, and possibly …

Sepsis and septic shock are the most common causes of acute kidney injury (AKI) in the
intensive care unit, and mortality remains high despite improvements in our ability to support …

EDITOR: Fauli and colleagues [1] are to be congratulated for their investigation into aprotinin
use at cardiac surgery and its effects on subclinically detected renal injury and dysfunction …

Background. Because of the well-known negative effects of carbon dioxide
pneumoperitoneum on the hemodynamic and respiratory system, it was questionable how …

Targeting greater pump flow and mean arterial pressure (MAP) during cardiopulmonary
bypass (CPB) could potentially alleviate renal hypoxia and reduce the risk of postoperative …

Acute kidney injury (AKI) is a common complication in critically ill patients and subsequently
worsens outcomes. Although many drugs to prevent and treat AKI have shown benefits in …

Background: The incidence of postoperative acute kidney injury (AKI) is predominantly
determined by renal hemodynamics. Beside arterial blood pressure, the role of factors …

Renal ischaemia involves a cascade of events with many causes, and ischaemic renal injury
is a frequent clinical problem, associated with high mortality [1]. In recent years, there have …

Background The precise physiologic consequences of insufflating carbon dioxide into the
abdominal cavity during laparoscopy are not yet fully understood. This systematic review …

An animal model was established to study the effects of elevated intra-abdominal pressure
(IAP) on systemic and renal hemodynamics during laparoscopy. In a pilot study in five dogs …