Leptin is a hormone primarily produced by the adipose tissue in proportion to the size of fat
stores, with a primary function in the control of lipid reserves. Besides adipose tissue, leptin …

Leptin is a master regulator of energy balance and body adiposity. Additionally, leptin exerts
important control on glucose homeostasis, thermogenesis, autonomic nervous system and …

The fat‐derived hormone, leptin, is well known to regulate body weight. However, there is
now substantial evidence that leptin also plays a primary role in the regulation of glucose …

Obesity results from an abnormal accumulation of fat in the white adipose tissue. Recent
research utilizing genetic models of obesity in rodents has implicated a major role of leptin …

The discovery of leptin was intrinsically associated with its ability to regulate body weight.
However, the effects of leptin are more far-reaching and include profound glucose-lowering …

Leptin is an adipocyte-derived hormone that primarily acts in the hypothalamus and plays a
key role in the regulation of food intake, body weight, energy expenditure and …

The peptide hormone leptin regulates food intake, body mass, and reproductive function and
plays a role in fetal growth, proinflammatory immune responses, angiogenesis and lipolysis …

The adipocyte-derived hormone, leptin, regulates food intake and systemic fuel metabolism;
ob/ob mice, which lack functional leptin, exhibit an obesity syndrome that is similar to morbid …

Historically, adipose tissue was considered to be a passive storage vessel discharging
nutrients in times of famine and accumulating fat in times of surfeit. This view changed with …

Since its discovery as an adipocyte-secreted hormone, leptin has been found to impact food
intake, energy homeostasis, and metabolism through its effects on the central nervous …