Poor recovery of muscle size and strength with aging coincides with a dysregulated
macrophage response during the early stages of regrowth. Immunomodulation in the form of …

Poor recovery of muscle size and strength with aging coincides with a dysregulated
macrophage response during the early stages of regrowth. Immunomodulation in the form of …

Impaired recovery of aged muscle following a disuse event is an unresolved issue facing the
older adult population. Although investigations in young animals have suggested that rapid …

Aging coincides with a higher frequency of muscle disuse and recovery events (due to
illness, surgery, pain) that are likely to lead to rapid loss of muscle mass and strength. Full …

Skeletal muscle regeneration that follows acute injury is strongly influenced by interactions
with immune cells that invade and proliferate in the damaged tissue. Discoveries over the …

Skeletal muscle injury in aged rodents is characterized by an asynchronous infiltration of pro-
and anti-inflammatory macrophage waves, leading to improper and incomplete …

The skeletal muscle is a dynamic organ composed of contractile muscle fibers, connective
tissues, blood vessels and nerve endings. Its main function is to provide motility to the body …

Aging is associated with diminished muscle mass, reductions in muscle stem cell functions,
and increased muscle fibrosis. The immune system, especially macrophages, can have …

Aging is associated with a loss of skeletal muscle mass and strength. Mechanistic
approaches to enhance muscle recovery in aging are non-existent. Macrophages play a …

Recruited immune cells play a critical role in muscle repair, in part by interacting with local
stem cell populations to regulate muscle regeneration. How aging affects their …