The motor cortex controls skilled arm movement by sending temporal patterns of activity to
lower motor centres. Local cortical dynamics are thought to shape these patterns throughout …

Activity in motor cortex predicts specific movements seconds before they occur, but how this
preparatory activity relates to upcoming movements is obscure. We dissected the conversion …

Activity in the motor cortex predicts movements, seconds before they are initiated. This
preparatory activity has been observed across cortical layers, including in descending …

Persistent and ramping neural activity in the frontal cortex anticipates specific movements,,,,–
. Preparatory activity is distributed across several brain regions,, but it is unclear which brain …

The brain's remarkable ability to learn and execute various motor behaviours harnesses the
capacity of neural populations to generate a variety of activity patterns. Here we explore …

Neural activity maintains representations that bridge past and future events, often over many
seconds. Network models can produce persistent and ramping activity, but the positive …

Most theories of motor cortex have assumed that neural activity represents movement
parameters. This view derives from what is known about primary visual cortex, where neural …

The motor cortex is capable of reliably driving complex movements, yet exhibits
considerable plasticity during motor learning,,,,,,,. These observations suggest that the …

For goal-directed behaviour it is critical that we can both select the appropriate action and
learn to modify the underlying movements (for example, the pitch of a note or velocity of a …

The brain generates complex sequences of movements that can be flexibly configured
based on behavioural context or real-time sensory feedback, but how this occurs is not fully …