The role of the microbiota in periodontal disease

MA Curtis, PI Diaz, TE Van Dyke - Periodontology 2000, 2020 - Wiley Online Library
The last decade has witnessed unparalleled advances in our understanding of the
complexity of the oral microbiome and the compositional changes that occur in subgingival …

Lessons learned and unlearned in periodontal microbiology

R Teles, F Teles, J Frias‐Lopez, B Paster… - Periodontology …, 2013 - Wiley Online Library
Periodontal diseases are initiated by bacterial species living in polymicrobial biofilms at or
below the gingival margin and progress largely as a result of the inflammation elicited by …

Microbial transitions from health to disease

S Joseph, MA Curtis - Periodontology 2000, 2021 - Wiley Online Library
Recent advances in our understanding of the microbial populations that colonize the human
mouth, their acquisition, interdependency, and coevolution with the host, bring a different …

Host modulation: controlling the inflammation to control the infection

PM Bartold, TE Van Dyke - Periodontology 2000, 2017 - Wiley Online Library
Historically, periodontal disease (gingivitis and periodontitis) has been recognized as being
primarily of bacterial origin. However, recent evidence indicates that while bacteria are …

Dysbiosis revisited: Understanding the role of the oral microbiome in the pathogenesis of gingivitis and periodontitis: A critical assessment

FA Scannapieco… - Journal of …, 2021 - Wiley Online Library
This commentary provides background, historical context, and a critical assessment of the
concept that microbial dysbiosis drives the pathogenesis of periodontal diseases. It is long …

Microbial protection and virulence in periodontal tissue as a function of polymicrobial communities: symbiosis and dysbiosis

FA Roberts, RP Darveau - Periodontology 2000, 2015 - Wiley Online Library
This review discusses polymicrobial interactions with the host in both health and disease. As
our ability to identify specific bacterial clonal types, with respect to their abundance and …

[PDF][PDF] Modulation of the innate immune response within the periodontium

DR Dixon, BW Bainbridge, RP Darveau - Periodontology 2000, 2004 - academia.edu
Within the periodontium, the characteristic shift in microbial compositions that occurs during
the transition from health to disease has been well documented (132, 206). Concurrently, it …

The oral microbiome: Role of key organisms and complex networks in oral health and disease

L Sedghi, V DiMassa, A Harrington… - Periodontology …, 2021 - Wiley Online Library
States of oral health and disease reflect the compositional and functional capacities of, as
well as the interspecies interactions within, the oral microbiota. The oral cavity exists as a …

An appraisal of the role of specific bacteria in the initial pathogenesis of periodontitis

PM Bartold, TE Van Dyke - Journal of clinical periodontology, 2019 - Wiley Online Library
Background Historically, inflammatory periodontal diseases (gingivitis and periodontitis)
have been recognized as being primarily of bacterial origin. Bacteria are necessary for …

Microbial signatures of health, gingivitis, and periodontitis

L Abusleme, A Hoare, BY Hong, PI Diaz - Periodontology 2000, 2021 - Wiley Online Library
The subgingival crevice harbors diverse microbial communities. Shifts in the composition of
these communities occur with the development of gingivitis and periodontitis, which are …