Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway

F Gao, B Zuo, Y Wang, S Li, J Yang, D Sun - Life sciences, 2020 - Elsevier
Aims To investigate the protective function of exosomes from adipose tissue-derived
mesenchymal stem cells (AMSCs) in sepsis-induced acute kidney injury (AKI) in mice and …

Exosomes derived from mesenchymal stem cells ameliorate renal ischemic-reperfusion injury through inhibiting inflammation and cell apoptosis

L Li, R Wang, Y Jia, R Rong, M Xu, T Zhu - Frontiers in Medicine, 2019 - frontiersin.org
This study aimed to investigate the underlying mechanism of mesenchymal stem cells
(MSCs) on protection of renal ischemia reperfusion injury (IRI). Exosomes originated from …

[HTML][HTML] Exosomes from adipose-derived stem cells inhibit inflammation and oxidative stress in LPS-acute kidney injury

W Zhang, J Zhang, H Huang - Experimental cell research, 2022 - Elsevier
Acute renal damage presents a significant danger to kidney health. Previous research has
found that acute kidney injury shows high levels of oxidative stress and inflammation caused …

Mesenchymal stem cells-derived exosomes ameliorate ischemia/reperfusion induced acute kidney injury in a porcine model

J Huang, H Cao, B Cui, X Ma, L Gao, C Yu… - Frontiers in cell and …, 2022 - frontiersin.org
Exosomes are membrane-enclosed vesicles secreted by cells, containing a variety of
biologically active ingredients including proteins, nucleic acids and lipids. In this study, we …

CCR2 positive exosome released by mesenchymal stem cells suppresses macrophage functions and alleviates ischemia/reperfusion‐induced renal injury

B Shen, J Liu, F Zhang, Y Wang, Y Qin… - Stem cells …, 2016 - Wiley Online Library
Mesenchymal stem cells (MSCs) derived exosomes have been shown to have protective
effects on the kidney in ischemia/reperfusion‐induced renal injury. However, the key …

Reproducible large-scale isolation of exosomes from adipose tissue-derived mesenchymal stem/stromal cells and their application in acute kidney injury

JH Lee, DH Ha, H Go, J Youn, H Kim, RC Jin… - International Journal of …, 2020 - mdpi.com
Acute kidney injury (AKI) is a fatal medical episode caused by sudden kidney damage or
failure, leading to the death of patients within a few hours or days. Previous studies …

Study of immunomodulatory effects of mesenchymal stem cell-derived exosomes in a mouse model of LPS induced systemic inflammation

F Eshghi, S Tahmasebi, M Alimohammadi, S Soudi… - Life Sciences, 2022 - Elsevier
Background Sepsis is a debilitating systemic inflammation that resulted from infection or
injury. Despite many advances in treatment, the resulting mortality rate has remained high …

Macrophage-derived exosomes mediate glomerular endothelial cell dysfunction in sepsis-associated acute kidney injury

H Xiang, Z Xu, C Zhang, J Xiong - Cell & bioscience, 2023 - Springer
Background Sepsis-associated AKI has been shown to be related to sepsis mortality.
Macrophage activation and endothelial cell damage are involved in the progression of …

[HTML][HTML] Adipose-derived mesenchymal stem cell-derived exosomes alleviate overwhelming systemic inflammatory reaction and organ damage and improve outcome …

CL Chang, PH Sung, KH Chen, PL Shao… - American journal of …, 2018 - ncbi.nlm.nih.gov
This study tested the hypothesis that healthy adipose-derived mesenchymal stem cell
(ADMSC)-derived exosomes (HMSC EXO) and apoptotic (A)(induced by 12 h hypoxia/12 h …

Exosomes from human‐bone‐marrow‐derived mesenchymal stem cells protect against renal ischemia/reperfusion injury via transferring miR‐199a‐3p

G Zhu, L Pei, F Lin, H Yin, X Li, W He… - Journal of cellular …, 2019 - Wiley Online Library
Renal ischemia/reperfusion (I/R) injury is the main reason for acute kidney injury (AKI) and is
closely related to high morbidity and mortality. In this study, we found that exosomes from …