Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway
F Gao, B Zuo, Y Wang, S Li, J Yang, D Sun - Life sciences, 2020 - Elsevier
Aims To investigate the protective function of exosomes from adipose tissue-derived
mesenchymal stem cells (AMSCs) in sepsis-induced acute kidney injury (AKI) in mice and …
mesenchymal stem cells (AMSCs) in sepsis-induced acute kidney injury (AKI) in mice and …
Exosomes derived from mesenchymal stem cells ameliorate renal ischemic-reperfusion injury through inhibiting inflammation and cell apoptosis
This study aimed to investigate the underlying mechanism of mesenchymal stem cells
(MSCs) on protection of renal ischemia reperfusion injury (IRI). Exosomes originated from …
(MSCs) on protection of renal ischemia reperfusion injury (IRI). Exosomes originated from …
[HTML][HTML] Exosomes from adipose-derived stem cells inhibit inflammation and oxidative stress in LPS-acute kidney injury
W Zhang, J Zhang, H Huang - Experimental cell research, 2022 - Elsevier
Acute renal damage presents a significant danger to kidney health. Previous research has
found that acute kidney injury shows high levels of oxidative stress and inflammation caused …
found that acute kidney injury shows high levels of oxidative stress and inflammation caused …
Mesenchymal stem cells-derived exosomes ameliorate ischemia/reperfusion induced acute kidney injury in a porcine model
J Huang, H Cao, B Cui, X Ma, L Gao, C Yu… - Frontiers in cell and …, 2022 - frontiersin.org
Exosomes are membrane-enclosed vesicles secreted by cells, containing a variety of
biologically active ingredients including proteins, nucleic acids and lipids. In this study, we …
biologically active ingredients including proteins, nucleic acids and lipids. In this study, we …
CCR2 positive exosome released by mesenchymal stem cells suppresses macrophage functions and alleviates ischemia/reperfusion‐induced renal injury
B Shen, J Liu, F Zhang, Y Wang, Y Qin… - Stem cells …, 2016 - Wiley Online Library
Mesenchymal stem cells (MSCs) derived exosomes have been shown to have protective
effects on the kidney in ischemia/reperfusion‐induced renal injury. However, the key …
effects on the kidney in ischemia/reperfusion‐induced renal injury. However, the key …
Reproducible large-scale isolation of exosomes from adipose tissue-derived mesenchymal stem/stromal cells and their application in acute kidney injury
Acute kidney injury (AKI) is a fatal medical episode caused by sudden kidney damage or
failure, leading to the death of patients within a few hours or days. Previous studies …
failure, leading to the death of patients within a few hours or days. Previous studies …
Study of immunomodulatory effects of mesenchymal stem cell-derived exosomes in a mouse model of LPS induced systemic inflammation
Background Sepsis is a debilitating systemic inflammation that resulted from infection or
injury. Despite many advances in treatment, the resulting mortality rate has remained high …
injury. Despite many advances in treatment, the resulting mortality rate has remained high …
Macrophage-derived exosomes mediate glomerular endothelial cell dysfunction in sepsis-associated acute kidney injury
H Xiang, Z Xu, C Zhang, J Xiong - Cell & bioscience, 2023 - Springer
Background Sepsis-associated AKI has been shown to be related to sepsis mortality.
Macrophage activation and endothelial cell damage are involved in the progression of …
Macrophage activation and endothelial cell damage are involved in the progression of …
[HTML][HTML] Adipose-derived mesenchymal stem cell-derived exosomes alleviate overwhelming systemic inflammatory reaction and organ damage and improve outcome …
CL Chang, PH Sung, KH Chen, PL Shao… - American journal of …, 2018 - ncbi.nlm.nih.gov
This study tested the hypothesis that healthy adipose-derived mesenchymal stem cell
(ADMSC)-derived exosomes (HMSC EXO) and apoptotic (A)(induced by 12 h hypoxia/12 h …
(ADMSC)-derived exosomes (HMSC EXO) and apoptotic (A)(induced by 12 h hypoxia/12 h …
Exosomes from human‐bone‐marrow‐derived mesenchymal stem cells protect against renal ischemia/reperfusion injury via transferring miR‐199a‐3p
G Zhu, L Pei, F Lin, H Yin, X Li, W He… - Journal of cellular …, 2019 - Wiley Online Library
Renal ischemia/reperfusion (I/R) injury is the main reason for acute kidney injury (AKI) and is
closely related to high morbidity and mortality. In this study, we found that exosomes from …
closely related to high morbidity and mortality. In this study, we found that exosomes from …
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