Red-emissive triplex-forming PNA probes carrying cyanine base surrogates for fluorescence sensing of double-stranded RNA

T Chiba, T Sato, Y Sato, S Nishizawa - Organic & Biomolecular …, 2017 - pubs.rsc.org
Red-emissive triplex-forming PNA probes carrying cyanine base surrogates for fluorescence
sensing of double-stranded RNA - Organic & Biomolecular Chemistry (RSC Publishing) …

Triplex-forming peptide nucleic acid probe having thiazole orange as a base surrogate for fluorescence sensing of double-stranded RNA

T Sato, Y Sato, S Nishizawa - Journal of the American Chemical …, 2016 - ACS Publications
We have developed a new fluorescent sensing probe for double-stranded RNA (dsRNA) by
integrating thiazole orange (TO) as a base surrogate into triplex-forming PNA. Our probe …

Design of fluorescent peptide nucleic acid probes carrying cyanine dyes for targeting double-stranded RNAs for analytical applications

Y Sato - Bulletin of the Chemical Society of Japan, 2020 - academic.oup.com
With the increasing knowledge about the diverse roles of RNAs within cells, much attention
has been paid to the development of RNA-binding fluorescent probes for the study of RNA …

Abasic site-binding ligands conjugated with cyanine dyes for “off–on” fluorescence sensing of orphan nucleobases in DNA duplexes and DNA–RNA hybrids

Y Sato, M Kudo, Y Toriyabe, S Kuchitsu… - Chemical …, 2014 - pubs.rsc.org
Abasic site-binding ligands conjugated with cyanine dyes for “off–on” fluorescence sensing of
orphan nucleobases in DNA duplexes and DNA–RNA hybrids - Chemical Communications …

Sequence-and structure-specific probing of RNAs by short nucleobase-modified dsRNA-binding PNAs incorporating a fluorescent light-up uracil analog

MS Krishna, DFK Toh, Z Meng, AAL Ong… - Analytical …, 2019 - ACS Publications
RNAs are emerging as important biomarkers and therapeutic targets. The strategy of directly
targeting double-stranded RNA (dsRNA) by triplex-formation is relatively underexplored …

Fluorescent 2‐Aminopyridine Nucleobases for Triplex‐Forming Peptide Nucleic Acids

SK Cheruiyot, E Rozners - ChemBioChem, 2016 - Wiley Online Library
Abstract Development of new fluorescent peptide nucleic acids (PNAs) is important for
fundamental research and practical applications. The goal of this study was the design of …

Double‐Stranded RNA‐Specific Templated Reaction with Triplex Forming PNA

KT Kim, D Chang, N Winssinger - Helvetica Chimica Acta, 2018 - Wiley Online Library
RNA, originally perceived as a simple information transfer biopolymer, is emerging as an
important regulator in cellular processes. A number of non‐coding RNA s are double …

A highly fluorescent nucleoside analog based on thieno [3, 4-d] pyrimidine senses mismatched pairing

SG Srivatsan, H Weizman, Y Tor - Organic & biomolecular chemistry, 2008 - pubs.rsc.org
A highly fluorescent nucleoside analog based on thieno[3,4- d ]pyrimidine senses mismatched
pairing - Organic & Biomolecular Chemistry (RSC Publishing) DOI:10.1039/B801054D Royal …

Dual sensing of hairpin and quadruplex DNA structures using multicolored peptide nucleic acid fluorescent probes

G Koripelly, K Meguellati, S Ladame - Bioconjugate chemistry, 2010 - ACS Publications
Synthesis of water-soluble 5-mer peptide nucleic acids (PNAs) functionalized at their 5′-
and 3′-ends with two original precursors of pentamethine cyanine dye synthesis is …

Optimization of the Alkyl Linker of TO Base Surrogate in Triplex‐Forming PNA for Enhanced Binding to Double‐Stranded RNA

T Sato, Y Sato, S Nishizawa - Chemistry–A European Journal, 2017 - Wiley Online Library
A series of triplex‐forming peptide nucleic acid (TFP) probes carrying a thiazole orange (TO)
base surrogate through an alkyl linker was synthesized, and the interactions between these …