Cancer growth is dependent on angiogenesis, the formation of new blood vessels, which
represents a hallmark of cancer. After this concept was established in the 1970s, inhibition of …

The recognition that angiogenesis is a key early event in tumor progression and metastasis
has led to the development of new strategies for cancer therapy. The generation of a new …

Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …

Advances in the knowledge of the main hallmarks of cancer will provide the basis for the
identification and development of therapeutic strategies to either prevent the occurrence of …

The potential to block tumor growth by inhibition of the neoangiogenic process represents
an intriguing approach to the treatment of solid tumors. The high proliferation rate in the …

Healthy individuals can harbour microscopic tumours and dysplastic foci in different organs
in an undetectable and asymptomatic state for many years. These lesions do not progress in …

Tumor angiogenesis is critically important for the growth of solid tumors as tumors remain in
dormant phase for a long time in the absence of the initiation of blood vessel formation …

Angiogenesis, the growth of new capillaries from pre-existing vessels, is closely related to
essential physiological processes for example: embryogenesis, reproductive cycle, and …

Cancer prevention is fast emerging as a discipline with a promising potential.
Chemoprevention has its rationale ‍in the multistage process of carcinogenesis which …

Angiogenesis—process of new blood-vessel growth from existing vasculature—is an
integral part of both normal developmental processes and numerous pathologies such as …