In nonalcoholic fatty liver disease (NAFLD), triglycerides accumulate within the liver because
the rates of fatty acid accrual by uptake from plasma and de novo synthesis exceed …

Thioesterase superfamily member 1 (Them1) is an acyl-CoA thioesterase that is highly
expressed in brown adipose tissue, where it functions to suppress energy expenditure …

Background and Aims Thioesterase superfamily member 2 (Them2) is highly expressed in
liver and oxidative tissues, where it hydrolyzes long‐chain fatty acyl‐CoA esters to free fatty …

Members of the acyl-CoA thioesterase (Acot) gene family catalyze the hydrolysis of fatty acyl-
CoAs, but their biological functions remain unknown. Thioesterase superfamily member 2 …

Thioesterase superfamily member 2 (Them2) is a mitochondrion-associated long-chain fatty
acyl coenzyme A (CoA) thioesterase that is highly expressed in the liver and oxidative …

Mammalian acyl-CoA thioesterases (Acots) catalyze the hydrolysis of fatty acyl-CoAs to form
free fatty acids plus CoA, but their metabolic functions remain undefined. Thioesterase …

Thioesterase superfamily member 1 (Them1; synonyms acyl-CoA thioesterase 11 and
StarD14) is highly expressed in brown adipose tissue and limits energy expenditure in mice …

Objective Non-shivering thermogenesis in brown adipose tissue (BAT) plays a central role in
energy homeostasis. Thioesterase superfamily member 1 (Them1), a BAT-enriched long …

Members of the acyl-CoA thioesterase (Acot) gene family hydrolyze fatty acyl-CoAs, but their
biological functions remain incompletely understood. Thioesterase superfamily member 2 …

Nonshivering thermogenesis occurs in brown adipose tissue to generate heat in response to
cold ambient temperatures. Thioesterase superfamily member 1 (Them1) is transcriptionally …