Mechanisms in endocrinology: metabolic and body composition effects of newer antiretrovirals in HIV-infected patients

S Srinivasa, SK Grinspoon - European journal of endocrinology, 2014 - academic.oup.com
In the absence of a cure, HIV-infected patients are being successfully treated with
antiretroviral therapies (ART) and living longer. Indeed, an increasing number of HIV …

Therapy insight: body-shape changes and metabolic complications associated with HIV and highly active antiretroviral therapy

J Falutz - Nature Clinical Practice Endocrinology & Metabolism, 2007 - nature.com
Increasingly effective therapies for HIV infection are now available. These treatments,
referred to collectively as highly active antiretroviral therapy, comprise various combinations …

Management of the metabolic effects of HIV and HIV drugs

TT Brown, MJ Glesby - Nature reviews endocrinology, 2012 - nature.com
Morphologic and metabolic abnormalities, including subcutaneous adipose tissue wasting,
central adipose tissue accumulation, dyslipidemia and disorders of glucose metabolism are …

Human immunodeficiency virus and highly active antiretroviral therapy–associated metabolic disorders and risk factors for cardiovascular disease

E Anuurad, A Semrad, L Berglund - Metabolic Syndrome and …, 2009 - liebertpub.com
The successful introduction of highly active antiretroviral therapy (HAART), a combination of
potent antiretroviral agents, including protease inhibitors, nucleoside reverse transcriptase …

Body composition and metabolic changes in HIV-infected patients

TL Stanley, SK Grinspoon - Journal of Infectious Diseases, 2012 - academic.oup.com
As antiretroviral therapy has decreased human immunodeficiency virus (HIV)–associated
mortality, cardiometabolic abnormalities have become increasingly apparent in HIV-infected …

Lipodystrophy and metabolic disorders as complication of antiretroviral therapy of HIV infection

A Holstein, A Plaschke… - Experimental and clinical …, 2001 - thieme-connect.com
Peripheral lipodystrophy, central adiposity, hyperlipidaemia, insulin resistance, and diabetes
mellitus, in varying constellations, are frequent complications of highly active antiretroviral …

Metabolic complications and glucose metabolism in HIV infection: a review of the evidence

AL Willig, ET Overton - Current Hiv/aids Reports, 2016 - Springer
HIV infection and antiretroviral therapy (ART) use are associated with perturbations in
glucose and lipid metabolism. Increasing incidence of diabetes, cardiovascular disease, and …

The effects of HIV-1 infection on endocrine organs

TT Brown - Best Practice & Research Clinical Endocrinology & …, 2011 - Elsevier
Early in the HIV epidemic, multiple endocrine and metabolic abnormalities were observed in
HIV-infected patients. These abnormalities were either related glandular infection or …

Metabolic consequences of antiretroviral therapy

CE Diggins, SC Russo, J Lo - Current HIV/AIDS Reports, 2022 - Springer
Abstract Purpose of Review This review reports on published studies describing metabolic
changes associated with antiretroviral therapy (ART) to treat HIV disease including a …

Insulin resistance in HIV-patients: causes and consequences

MN Pedro, GZ Rocha, D Guadagnini… - Frontiers in …, 2018 - frontiersin.org
Here we review how immune activation and insulin resistance contribute to the metabolic
alterations observed in HIV-infected patients, and how these alterations increase the risk of …