Genetic linkage analysis with dyslexia: evidence for linkage of spelling disability to chromosome 15

MM Nöthen, G Schulte-Koerne, T Grimm… - European child & …, 1999 - Springer
Dyslexia (reading and spelling disability) is one of the most frequently diagnosed disorders
in childhood. Twin studies of dyslexia have indicated that deficits in spelling are substantially …

Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia

N Cope, D Harold, G Hill, V Moskvina… - The American Journal of …, 2005 - cell.com
Linkage between developmental dyslexia (DD) and chromosome 6p has been replicated in
a number of independent samples. Recent attempts to identify the gene responsible for the …

The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319 , a novel gene involved in neuronal migration

S Paracchini, A Thomas, S Castro, C Lai… - Human molecular …, 2006 - academic.oup.com
Dyslexia is one of the most prevalent childhood cognitive disorders, affecting∼ 5% of school-
age children. We have recently identified a risk haplotype associated with dyslexia on …

Susceptibility loci for distinct components of developmental dyslexia on chromosomes 6 and 15.

EL Grigorenko, FB Wood, MS Meyer… - American journal of …, 1997 - ncbi.nlm.nih.gov
Six extended dyslexic families with at least four affected individuals were genotyped with
markers in three chromosomal regions: 6p23-p21. 3, 15pter-qter, and 16pter-qter. Five …

Identification of novel dyslexia candidate genes through the analysis of a chromosomal deletion

G Poelmans, JJM Engelen… - American Journal of …, 2009 - Wiley Online Library
Dyslexia is the most common childhood learning disorder and it is a significantly heritable
trait. At least nine chromosomal loci have been linked to dyslexia, and additional …

Further evidence that the KIAA0319 gene confers susceptibility to developmental dyslexia

D Harold, S Paracchini, T Scerri, M Dennis… - Molecular …, 2006 - nature.com
The DYX2 locus on chromosome 6p22. 2 is the most replicated region of linkage to
developmental dyslexia (DD). Two candidate genes within this region have recently been …

Fine mapping of the chromosome 2p12-16 dyslexia susceptibility locus: quantitative association analysis and positional candidate genes SEMA4F and OTX1

C Francks, SE Fisher, RK Olson… - Psychiatric …, 2002 - journals.lww.com
A locus on chromosome 2p12-16 has been implicated in dyslexia susceptibility by two
independent linkage studies, including our own study of 119 nuclear twin-based families …

Evaluation of candidate genes for DYX1 and DYX2 in families with dyslexia

Z Brkanac, NH Chapman… - American Journal of …, 2007 - Wiley Online Library
Dyslexia is a common heterogeneous disorder with a significant genetic component.
Multiple studies have replicated the evidence for linkage between variously defined …

Evidence for a susceptibility locus on chromosome 6q influencing phonological coding dyslexia

TL Petryshen, BJ Kaplan, M Fu Liu… - American journal of …, 2001 - Wiley Online Library
A linkage study of 96 dyslexia families containing at least two affected siblings (totaling 877
individuals) has found evidence for a dyslexia susceptibility gene on chromosome 6q11. 2 …

Evidence for major gene transmission of developmental dyslexia

BF Pennington, JW Gilger, D Pauls, SA Smith… - Jama, 1991 - jamanetwork.com
Objective.—There is strong evidence that developmental dyslexia is both familial and
heritable, but the mode of genetic transmission has remained unclear. In this article, we …