Vascular endothelial growth factor‐modified macrophages accelerate reendothelialization and attenuate neointima formation after arterial injury in atherosclerosis …

D Yan, D Zhang, L Lu, H Qiu… - Journal of Cellular …, 2019 - Wiley Online Library
Vascular endothelial growth factor (VEGF) is a promising molecule for cardiovascular
diseases therapy. But lack of a targeted delivery system limits its translation into clinical …

[HTML][HTML] The role of angiogenesis in wound healing, scarring and tissue regeneration

FV Lali, AD Metcalfe - PMFA News, 2014 - thepmfajournal.com
In the UK alone there are 175,000 people who visit Accident & Emergency departments with
burns each year. This results in around 13,000 hospital admissions, of which 1000 are due …

An in vitro model of angiogenesis during wound healing provides insights into the complex role of cells and factors in the inflammatory and proliferation phase

S Beyer, M Koch, YH Lee, F Jung, A Blocki - International journal of …, 2018 - mdpi.com
Successful vascularization is essential in wound healing, the histo-integration of
biomaterials, and other aspects of regenerative medicine. We developed a functional in vitro …

[HTML][HTML] Mechanism of sustained release of vascular endothelial growth factor in accelerating experimental diabetic healing

H Brem, A Kodra, MS Golinko, H Entero… - Journal of investigative …, 2009 - Elsevier
In this study, we hypothesize that local sustained release of vascular endothelial growth
factor (VEGF), using adenovirus vector (ADV)-mediated gene transfer, accelerates …

Therapeutic Angiogenesis in Wounds: The Influence of Growth Factors at a Muscle Flap—Ischemic Tissue Interface

KJ Walgenbach, G Bruenagel, JE Lovett… - Biological matrices and …, 1998 - Springer
After having demonstrated that the transfer of a well perfused muscle flap predictably
enhances the revascularization of ischemic tissue, further studies revealed the presence of …

[HTML][HTML] Expressional regulation of angiopoietin-1 and-2 and the tie-1 and-2 receptor tyrosine kinases during cutaneous wound healing: a comparative study of normal …

H Kämpfer, J Pfeilschifter, S Frank - Laboratory investigation, 2001 - Elsevier
It has become evident that a closely regulated presence of vascular endothelial growth
factor (VEGF) and angiopoietin (Ang) factors determines the fate of blood vessel formation …

Angiogenic effects of injected VEGF165 and sVEGFR-1 (sFLT-1) in a rat flap model

HG Machens, J Salehi, H Weich, S Münch… - Journal of Surgical …, 2003 - Elsevier
Background. Injections of single-dose vascular endothelial growth factor (VEGF) 165 have
been advocated as a therapeutic tool for angiogenesis in ischemic flaps. We challenged this …

VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain

ZG Zhang, L Zhang, Q Jiang, R Zhang… - The Journal of …, 2000 - Am Soc Clin Investig
VEGF is a secreted mitogen associated with angiogenesis and is also a potent vascular
permeability factor. The biological role of VEGF in the ischemic brain remains unknown. This …

Vascular endothelial growth factor induces extracellular matrix proteins and osteopontin in the umbilical artery

M Infanger, J Grosse, K Westphal, A Leder… - Annals of vascular …, 2008 - Elsevier
Vascular endothelial growth factor (VEGF) is a mitogenic, angiogenic, and potent mediator
of vascular permeability. It plays a role in injuries, contributes to edema during the acute …

In vitro and ex vivo kinetic release profile of growth factors and cytokines from leucocyte-and platelet-rich fibrin (L-PRF) preparations

X Wang, MR Fok, G Pelekos, L Jin, MS Tonetti - Cells, 2022 - mdpi.com
L-PRF is an autologous blood-derived biomaterial (ABDB) capable of releasing biologically
active agents to promote healing. Little is known about its release profile of growth factors …