[HTML][HTML] How changes in brain activity and connectivity are associated with motor performance in people with MS

DS Peterson, BW Fling - NeuroImage: Clinical, 2018 - Elsevier
People with multiple sclerosis (MS) exhibit pronounced changes in brain structure, activity,
and connectivity. While considerable work has begun to elucidate how these neural …

Plasticity of the motor system in multiple sclerosis

D Zeller, J Classen - Neuroscience, 2014 - Elsevier
Multiple sclerosis (MS) is a chronic neurological disease characterized by inflammation and
degeneration within the CNS. Over the course of the disease, most MS patients successively …

A multicentre study of motor functional connectivity changes in patients with multiple sclerosis

P Valsasina, MA Rocca, M Absinta… - European Journal of …, 2011 - Wiley Online Library
In this multicentre study involving eight European centres, we characterized the spatial
pattern of functional connectivity (FC) in the sensorimotor network from 61 right‐handed …

Altered sensorimotor cortical oscillations in individuals with multiple sclerosis suggests a faulty internal model

DJ Arpin, E Heinrichs‐Graham… - Human brain …, 2017 - Wiley Online Library
Multiple sclerosis (MS) is a demyelinating disease that results in a broad array of symptoms,
including impaired motor performance. How such demyelination of fibers affects the inherent …

Abnormal connectivity of the sensorimotor network in patients with MS: a multicenter fMRI study

MA Rocca, M Absinta, P Valsasina… - Human brain …, 2009 - Wiley Online Library
In this multicenter study, we used dynamic causal modeling to characterize the
abnormalities of effective connectivity of the sensorimotor network in 61 patients with …

Expanded functional coupling of subcortical nuclei with the motor resting-state network in multiple sclerosis

AM Dogonowski, HR Siebner… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Background: Multiple sclerosis (MS) impairs signal transmission along cortico-cortical and
cortico-subcortical connections, affecting functional integration within the motor network …

Impairment of movement-associated brain deactivation in multiple sclerosis: further evidence for a functional pathology of interhemispheric neuronal inhibition

SC Manson, C Wegner, M Filippi, F Barkhof… - Experimental brain …, 2008 - Springer
Motor control demands coordinated excitation and inhibition across distributed brain
neuronal networks. Recent work has suggested that multiple sclerosis (MS) may be …

[HTML][HTML] Motor imagery as a function of disease severity in multiple sclerosis: an fMRI study

A Tacchino, C Saiote, G Brichetto… - Frontiers in human …, 2018 - frontiersin.org
Motor imagery (MI) is defined as mental execution without any actual movement. While
healthy adults usually show temporal equivalence, ie, isochrony, between the mental …

Evidence for widespread movement-associated functional MRI changes in patients with PPMS

MA Rocca, PM Matthews, D Caputo, A Ghezzi, A Falini… - Neurology, 2002 - AAN Enterprises
Background: Previous work has suggested that functional reorganization of cortical motor
areas might have a role in limiting the motor deficits in patients with MS. Objective: To test …

Functional cortical changes in patients with multiple sclerosis and nonspecific findings on conventional magnetic resonance imaging scans of the brain

MA Rocca, E Pagani, A Ghezzi, A Falini, M Zaffaroni… - Neuroimage, 2003 - Elsevier
Recent functional magnetic resonance imaging (fMRI) work has suggested that cortical
reorganisation might have an adaptive role in limiting the clinical impact of multiple sclerosis …