Strategies for control of trachoma: observational study with quantitative PCR

AW Solomon, MJ Holland, MJ Burton, SK West… - The Lancet, 2003 - thelancet.com
Background Antibiotics are an important part of WHO's strategy to eliminate trachoma as a
blinding disease by 2020. At present, who needs to be treated is unclear. We aimed to …

Trachoma prevalence and associated risk factors in the gambia and Tanzania: baseline results of a cluster randomised controlled trial

EM Harding-Esch, T Edwards, H Mkocha… - PLoS neglected …, 2010 - journals.plos.org
Background Blinding trachoma, caused by ocular infection with Chlamydia trachomatis, is
targeted for global elimination by 2020. Knowledge of risk factors can help target control …

Field evaluation of a rapid point-of-care assay for targeting antibiotic treatment for trachoma control: a comparative study

CEC Michel, AW Solomon, JPV Magbanua, PA Massae… - The Lancet, 2006 - thelancet.com
Background Trachoma results from repeated episodes of conjunctival infection with
Chlamydia trachomatis and is the leading infectious cause of blindness. To eliminate …

Azithromycin in control of trachoma

J Schachter, SK West, D Mabey, CR Dawson, L Bobo… - The Lancet, 1999 - thelancet.com
Background Trachoma is the leading cause of preventable blindness. Pogrammes to
prevent blindness due to trachoma are based on community-wide treatment with topical …

Active Trachoma and Ocular Chlamydia trachomatis Infection in Two Gambian Regions: On Course for Elimination by 2020?

EM Harding-Esch, T Edwards, A Sillah… - PLoS neglected …, 2009 - journals.plos.org
Background Trachoma has been endemic in The Gambia for decades. National trachoma
control activities have been in place since the mid-1980's, but with no mass antibiotic …

Re-emergence of Chlamydia trachomatis infection after mass antibiotic treatment of a trachoma-endemic Gambian community: a longitudinal study

MJ Burton, MJ Holland, P Makalo, EAN Aryee… - The Lancet, 2005 - thelancet.com
Background Community-wide mass antibiotic treatment is a central component of trachoma
control. The optimum frequency and duration of treatment are unknown. We measured the …

Can We Use Antibodies to Chlamydia trachomatis as a Surveillance Tool for National Trachoma Control Programs? Results from a District Survey

SK West, B Munoz, J Weaver, Z Mrango… - PLoS neglected …, 2016 - journals.plos.org
Background Trachoma is targeted for elimination by 2020. World Health Organization
advises districts to undertake surveillance when follicular trachoma (TF)< 5% in children 1–9 …

Infection with Chlamydia trachomatis after mass treatment of a trachoma hyperendemic community in Tanzania: a longitudinal study

SK West, B Munoz, H Mkocha, MJ Holland, A Aguirre… - The Lancet, 2005 - thelancet.com
Background Data from studies done in communities where trachoma is mesoendemic
suggest that ocular infection with Chlamydia trachomatis can be eliminated after one mass …

Trachoma

HR Taylor, MJ Burton, D Haddad, S West, H Wright - The Lancet, 2014 - thelancet.com
Trachoma is the most common infectious cause of blindness. Repeated episodes of
infection with Chlamydia trachomatis in childhood lead to severe conjunctival inflammation …

Trachoma

AW Solomon, MJ Burton, EW Gower… - Nature Reviews …, 2022 - nature.com
Trachoma is a neglected tropical disease caused by infection with conjunctival strains of
Chlamydia trachomatis. It can result in blindness. Pathophysiologically, trachoma is a …