Liver fibrosis is caused by a sustained wound healing response to chronic liver injury, and
the activation of insubstantial hepatic stellate cells (HSCs) is the key process involved. The …

Abstract Background and Aims Recent research shows that abnormal expression of
microRNA plays an important role in the process of hepatic fibrosis. miR-370 has been …

There has been an increasing number of studies about microRNAs as key regulators in the
development of hepatic fibrosis. Here, we demonstrate that miR‐542‐3p can promote …

Background/Aims: Recently, microRNAs (miRNAs) have been demonstrated to act as
regulators of activation of hepatic stellate cells (HSCs). It is well known that the main …

Hepatic fibrosis is a chronic inflammatory and reversible repair reaction of the liver under the
continuous action of virus or various injuries. In this study, we aimed at identifying the role of …

Background & Aims Hepatic fibrosis is characterized by hepatic stellate cell (HSC) activation
and transdifferentiation-mediated extracellular matrix (ECM) deposition, which both …

Estradiol (E2) is a major determinant of gender‐based differences in the development of
hepatic fibrosis. MicroRNAs (miRNAs) are endogenous 19‐25 nucleotide, noncoding, single …

Activation of hepatic stellate cells (HSC) plays a pivotal role in the development of hepatic
fibrosis. Transforming growth factor-β1 (TGF-β1) is considered to be the main stimuli factor …

Background & Aims Fibrosis, a cardinal feature of a dysfunctional liver, significantly
contributes to the ever-increasing mortality due to end-stage chronic liver diseases. The …

miR-125b is frequently dysregulated in different diseases. Activation of hepatic stellate cells
(HSCs) is a critical event during liver fibrogenesis. However, the function and its underlying …