White adipose tissue (WAT) produces interleukin-10 and other immune suppressors in
response to pathogen-associated molecular patterns (PAMPs). It also homes a subset of B …

Obesity is associated with a chronic inflammatory state, and adipocyte dysfunction is thought
to play a crucial role in this. Infection of adipose tissue may trigger the production of …

Objectives: In context of metabolic disease, adipocytes were shown to pathologically interact
with the immune system. When becoming obese, these cells drive inflammation in adipose …

The anti-inflammatory cytokine interleukin (IL)-10 plays an important role in the regulation of
host-immune responses. Here we studied the role IL-10 plays in host responses to …

Viral infections can disturb the functions of adipose tissues and thus result in metabolic
diseases. Polyinosinic‐polycytidylic acid (poly (I: C)), a synthetic analog of viral double …

Mounting evidence has established a role for chronic inflammation in the development of
obesity-induced insulin resistance, as genetic ablation of pro-inflammatory cytokines and …

Background: Various pathogens are implicated in the induction of obesity. Previous studies
have confirmed that human adenovirus 36 (Ad36) is associated with increased adiposity …

Adipose tissue macrophages are a heterogeneous collection of classically activated (M1)
and alternatively activated (M2) macrophages. Interleukin 10 (IL-10) is an anti-inflammatory …

White adipose tissue (WAT) is the source of pro-and anti-inflammatory cytokines and we
have recently shown that this tissue is a major source of the anti-inflammatory interleukin (IL) …

Obese adipose tissue (AT) is characterized by increased recruitment and infiltration of
multiple immune cell populations, in particular T cells (CD4+ or CD8+ subsets) and …