Performance of measurands in time-domain optical brain imaging: depth selectivity versus contrast-to-noise ratio

A Sudakou, L Yang, H Wabnitz… - Biomedical Optics …, 2020 - opg.optica.org
Time-domain optical brain imaging techniques introduce a number of different measurands
for analyzing absorption changes located deep in the tissue, complicated by superficial …

Performance assessment of time-domain optical brain imagers: a multi-laboratory study

H Wabnitz, A Jelzow, M Mazurenka… - … of Phantoms Used …, 2013 - spiedigitallibrary.org
Novel protocols were developed and applied in the European project “nEUROPt” to assess
and compare the performance of instruments for time-domain optical brain imaging and of …

Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol

H Wabnitz, DR Taubert, M Mazurenka… - … of biomedical optics, 2014 - spiedigitallibrary.org
Performance assessment of instruments devised for clinical applications is of key
importance for validation and quality assurance. Two new protocols were developed and …

Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol

H Wabnitz, A Jelzow, M Mazurenka… - … of biomedical optics, 2014 - spiedigitallibrary.org
The nEUROPt protocol is one of two new protocols developed within the European project
nEUROPt to characterize the performances of time-domain systems for optical imaging of …

Improved sensitivity to cerebral hemodynamics during brain activation with a time-gated optical system: analytical model and experimental validation

J Selb, JJ Stott, MA Franceschini… - … of biomedical optics, 2005 - spiedigitallibrary.org
Time domain (TD) diffuse optical measurement systems are being applied to neuroimaging,
where they can detect hemodynamics changes associated with cerebral activity. We show …

Depth selectivity in time-domain optical brain imaging based on time windows and moments of time-of-flight distributions

H Wabnitz, A Liebert, D Contini, L Spinelli… - Biomedical …, 2008 - opg.optica.org
Different approaches to discriminate between cerebral and extracerebral absorption
changes are compared by means of diffusion and Monte-Carlo simulations and applied to …

Time-gated optical system for depth-resolved functional brain imaging

J Selb, DK Joseph, DA Boas - Journal of biomedical optics, 2006 - spiedigitallibrary.org
We present a time-domain optical system for functional imaging of the adult head. We first
describe the instrument, which is based on a Ti: Sapphire pulsed laser (wavelength 750 …

Depth selectivity in time-domain fNIRS by analyzing moments and time windows

A Sudakou, H Wabnitz, L Yang… - … of Tissue XIV, 2021 - spiedigitallibrary.org
Time-domain fNIRS facilitates the elimination of the influence of extracerebral, systemic
effects on measured signals since it contains time-of-flight information that is related to the …

Assessment of basic instrumental performance of time-domain optical brain imagers

H Wabnitz, A Pifferi, A Torricelli… - … of Tissue IX, 2011 - spiedigitallibrary.org
To facilitate the design and optimization of instruments for time-domain optical brain imaging
within the European project" nEUROPt", the performance of various instruments is assessed …

Determination of absorption changes from moments of distributions of times of flight of photons: optimization of measurement conditions for a two-layered tissue model

A Liebert, H Wabnitz, C Elster - Journal of Biomedical Optics, 2012 - spiedigitallibrary.org
Time-resolved near-infrared spectroscopy allows for depth-selective determination of
absorption changes in the adult human head that facilitates separation between cerebral …