Antioxidant neuroprotection in Alzheimer's disease as preventive and therapeutic approach

C Behl, B Moosmann - Free Radical Biology and Medicine, 2002 - Elsevier
Various neurodegenerative disorders and syndromes are associated with oxidative stress.
The deleterious consequences of excessive oxidations and the pathophysiological role of …

Antioxidants as treatment for neurodegenerative disorders

B Moosmann, C Behl - Expert opinion on investigational drugs, 2002 - Taylor & Francis
Oxidative stress is a ubiquitously observed hallmark of neurodegenerative disorders.
Neuronal cell dysfunction and cell death due to oxidative stress may causally contribute to …

Oxidative stress in Alzheimer's disease: implications for prevention and therapy

C Behl - Alzheimer's Disease: Cellular and Molecular Aspects of …, 2005 - Springer
Oxidative stress is a marker of neurodegeneration and has been recently shown to be also
involved in the early stages of the pathogenesis of various neurodegenerative disorders. In …

Antioxidant treatment in Alzheimer's disease: current state

Y Gilgun-Sherki, E Melamed, D Offen - Journal of Molecular Neuroscience, 2003 - Springer
Accumulating data from experimental and human studies indicate that oxidative stress (OS)
plays a major role in the pathogenesis of Alzheimer's disease (AD). The production of …

Antioxidant therapies for Alzheimer′ s disease

Y Feng, X Wang - Oxidative medicine and cellular longevity, 2012 - Wiley Online Library
Alzheimer's disease (AD) is the most common neurodegenerative disease featuring
progressive impairments in memory, cognition, and behavior and ultimately leads to death …

Antioxidant properties of natural polyphenols and their therapeutic potentials for Alzheimer's disease

DY Choi, YJ Lee, JT Hong, HJ Lee - Brain research bulletin, 2012 - Elsevier
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease and most
common cause of dementia. However, there is no known way to halt or cure the …

Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches

C Behl - Progress in neurobiology, 1999 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with a deadly
outcome. AD is the leading cause of senile dementia and although the pathogenesis of this …

Oxidative stress in Alzheimer's disease: should we keep trying antioxidant therapies?

MES Ferreira, AS de Vasconcelos… - Cellular and molecular …, 2015 - Springer
The risk of chronic diseases such as Alzheimer's disease is growing as a result of the
continuous increasing average life span of the world population, a syndrome characterized …

Oxidative stress in alzheimer's disease: A review on emergent natural polyphenolic therapeutics

L Cassidy, F Fernandez, JB Johnson, M Naiker… - … therapies in medicine, 2020 - Elsevier
Objectives The aim of this research was to review the literature on Alzheimer's disease (AD)
with a focus on polyphenolics as antioxidant therapeutics. Design This review included a …

Antioxidants in Alzheimer's disease: Current therapeutic significance and future prospects

P Pritam, R Deka, A Bhardwaj, R Srivastava, D Kumar… - Biology, 2022 - mdpi.com
Simple Summary Alzheimer's disease (AD) is the most common neurodegenerative disease,
intensifying impairments in cognition, behavior, and memory. Histopathological AD …