Background The single-nucleotide polymorphism (SNP) rs11191548, near the CYP17A1
gene, has been identified as being associated with hypertension and systolic blood …

CYP17A1 gene encodes the cytochrome P450 enzyme CYP17A1, a key enzyme involved in
steroid metabolism. A single nucleotide polymorphism (SNP) near CYP17A1, rs11191548 …

Background: Hypertension is one of the leading causes of human death and disability.
CYP24A1 regulates vitamin D activity and is closely linked to hypertension. However, the …

The relationship between CYP17A1 genetic polymorphisms and essential hypertension
(EH) remains unclear. The aim of this study was to investigate the association of CYP17A1 …

The CYP17A1 gene, which encodes17α-hydroxylase and 17, 20-lyase, has been identified
as a common hypertension susceptibility locus in a European population. However, the …

Abstract Background The CYP17A1 gene has been identified to associate with hypertension
in Chinese population. However, the association between CYP17A1 polymorphisms and …

Objective: With the development of genome-wide association studies (GWAS) concerning
hypertension, a growing number of susceptibility genes related to hypertension have been …

Background: It has been suggested that the− 344C/T polymorphism in the CYP11B2 gene is
involved in the development of hypertension. However, the results have been inconsistent …

Variants of the human CYP4A11, which belongs to the cytochrome P450, family 4, have
been reported to be associated with hypertension in general populations. However, data in …

This study investigated the association between single-nucleotide polymorphisms (SNPs;
rs3808607 and rs1125226) within the CYP7A1 promoter and hypertension susceptibility in a …