Improved uptake and survival with systemic treatments for metastatic non-small cell lung cancer: younger versus older adults

B Leung, A Shokoohi, Z Al-Hashami, S Moore… - BMC cancer, 2023 - Springer
Background Over the past decade, there has been increasing availability of novel
therapeutics with improved tolerability and efficacy for advanced non-small cell lung cancer …

Does progress achieved in the treatment of patients with metastatic non‐small‐cell lung cancer reach the elderly population? A cohort study from a cancer centre from …

S Schmid, J Suipyte, C Herrmann… - European journal of …, 2020 - Wiley Online Library
Objective Treatment options for non‐small‐cell lung cancer (NSCLC) have been evolving.
The goal of our study was to evaluate whether novel therapeutics are used in the elderly …

Evolution of systemic treatment uptake and survival in advanced non-small cell lung cancer

S Stock-Martineau, K Laurie, M McKinnon, T Zhang… - Current oncology, 2020 - mdpi.com
Background: Non-small cell lung cancer (NSCLC) commonly presents at advanced stage.
We previously reported systemic treatment uptake in stage IV NSCLC climbing from …

[HTML][HTML] Uptake of novel systemic therapy: Real world patterns among adults with advanced non-small cell lung cancer

NM Carroll, J Eisenstein, AN Burnett-Hartman… - Cancer treatment and …, 2023 - Elsevier
Introduction/background Systemic treatment for advanced non-small cell lung cancer
(NSCLC) is shifting from platinum-based chemotherapy to immunotherapy and targeted …

The role for chemotherapy in 80 years and older patients with metastatic non-small cell lung cancer: A National cancer database analysis

Z Ahmed, K Kennedy, J Subramanian - Lung Cancer, 2021 - Elsevier
Background There are limited data on the role for chemotherapy in patients> 80 years old
with advanced stage non-small cell lung carcinoma (NSCLC). We used the National Cancer …

Real-world overview of therapeutic strategies and prognosis of older patients with advanced or metastatic non-small cell lung cancer from the ESME database

M Cabart, L Mourey, D Pasquier, S Schneider… - Journal of Geriatric …, 2024 - Elsevier
Abstract Introduction In France, 40% of patients diagnosed with lung cancer are≥ 70 years
old, but these are under-represented in clinical trials. Using data from the French …

Enrolment of older adults with advanced or metastatic non-small cell lung cancer in first-line clinical trials in the multicentre ESME cohort

M Bringuier, M Carton, D Debieuvre, D Pasquier… - Journal of Geriatric …, 2023 - Elsevier
Introduction There is a great need for data based on clinical trials for the older population in
order to improve treatment. Historically, the inclusion rate of older adults in clinical trials has …

[引用][C] Patients of all ages with advanced non‐small cell lung cancer are not receiving chemotherapy

MK Barton - CA: A Cancer Journal for Clinicians, 2015 - Wiley Online Library
Recent studies have revealed that few elderly patients receive chemotherapy for advanced
non-small cell lung cancer (NSCLC), even though it has been shown that the majority of …

Treatment patterns and clinical outcomes in patients with advanced non-small cell lung cancer initiating first-line treatment in the US community oncology setting: a …

E Nadler, B Arondekar, KM Aguilar, J Zhou… - Journal of Cancer …, 2021 - Springer
Purpose Treatments for advanced non-small cell lung cancer (NSCLC) have evolved to
include targeted and immuno-oncology therapies, which have demonstrated clinical benefits …

Patterns of care for older patients with stage IV non‐small cell lung cancer in the immunotherapy era

KL Kehl, MJ Hassett, D Schrag - Cancer Medicine, 2020 - Wiley Online Library
Background Historically, older patients with advanced lung cancer have often received no
systemic treatment. Immunotherapy has improved outcomes in clinical trials, but its …