Prognosis and improved outcomes in major depression: a review

C Kraus, B Kadriu, R Lanzenberger, CA Zarate Jr… - Focus, 2020 - Am Psychiatric Assoc
Treatment outcomes for major depressive disorder (MDD) need to be improved. Presently,
no clinically relevant tools have been established for stratifying subgroups or predicting …

[HTML][HTML] Prognosis and improved outcomes in major depression: a review

C Kraus, B Kadriu, R Lanzenberger… - Translational …, 2019 - nature.com
Abstract Treatment outcomes for major depressive disorder (MDD) need to be improved.
Presently, no clinically relevant tools have been established for stratifying subgroups or …

[HTML][HTML] Functional recovery in major depressive disorder: focus on early optimized treatment

J Habert, MA Katzman, OJ Oluboka… - The primary care …, 2016 - psychiatrist.com
Objective: This article presents the case that a more rapid, individualized approach to
treating major depressive disorder (MDD) may increase the likelihood of achieving full …

In adults with depression, does medication therapy directed by pharmacogenetic testing lead to better outcomes than nondirected medication therapy?

JS Anderson, TJ Satre - Evidence-Based Practice, 2021 - journals.lww.com
A2019 meta-analysis that included five randomized control trials (RCTs)(n51, 737)
evaluated the effectiveness of pharmacogenetic-guided treatment of major depressive …

[HTML][HTML] Challenges in treating patients with major depressive disorder: the impact of biological and social factors

S Sato, TL Yeh - CNS drugs, 2013 - Springer
Major depressive disorder (MDD) is frequently unrecognized and underdiagnosed by
clinicians and thus remains untreated or inappropriately treated in routine clinical practice …

[HTML][HTML] Effect of pharmacogenomics testing guiding on clinical outcomes in major depressive disorder: a systematic review and meta-analysis of RCT

X Wang, C Wang, Y Zhang, Z An - Bmc Psychiatry, 2023 - Springer
Background Pharmacogenomic testing guided treatment have been developed to guide
drug selection or conversion in major depressive disorder patients. Whether patients benefit …

[HTML][HTML] How to utilize clinical and genetic information for personalized treatment of major depressive disorder: step by step strategic approach

C Fabbri, A Serretti - Clinical Psychopharmacology and …, 2020 - ncbi.nlm.nih.gov
Depression is the single largest contributor to non-fatal health loss and affects 322 million
people globally. The clinical heterogeneity of this disorder shows biological correlates and it …

[HTML][HTML] The establishment of the objective diagnostic markers and personalized medical intervention in patients with major depressive disorder: rationale and …

X Lv, T Si, G Wang, H Wang, Q Liu, C Hu, J Wang, Y Su… - BMC psychiatry, 2016 - Springer
Background Major depressive disorders (MDD) is a common mental disorder with high
prevalence, frequent relapse and associated with heavy disease burden. Heritability …

The effect of pharmacogenomic testing on response and remission rates in the acute treatment of major depressive disorder: a meta-analysis

JD Rosenblat, Y Lee, RS McIntyre - Journal of affective disorders, 2018 - Elsevier
Background Pharmacogenomic testing has recently become scalable and available to guide
the treatment of major depressive disorder (MDD). The objective of the current meta-analysis …

Personalized medicine in major depressive disorder—opportunities and pitfalls

DB Miller, JP O'Callaghan - Metabolism, 2013 - Elsevier
The sequencing of the human genome in the early days of this millennium was greeted with
great fanfare as this accomplishment was expected to revolutionize medicine and result in …