Cryoablation with KCl Solution Enhances Necrosis and Apoptosis of HepG2 Liver Cancer Cells

M Chen, W Liu, B Liu - Annals of Biomedical Engineering, 2024 - Springer
Cryoablation has become a valuable treatment modality for the management of liver cancer.
However, one of the major challenges in cryosurgery is the incomplete cryodestruction near …

Regulating the cryo-freezing region of biological tissue with a controlled thermal device

X Zhao, KJ Chua - Medical Engineering & Physics, 2014 - Elsevier
Cryoablation is a minimally invasive technique that kills tissue in situ through freezing and is
used to destroy unresectable benign and malignant tumors. A key objective of this …

Physical observations on rapid freezing of tumour cells to-40 degrees C using differential scanning calorimetry

S El-Shakhs, S Shimi, EE Benson, L Newman… - Cryo …, 1998 - discovery.dundee.ac.uk
Cryoablation is now an established modality in treating liver tumours although local
recurrence of liver tumours after cryosurgery, remains a problem. Thus, the optimal, final …

[HTML][HTML] Percutaneous cryoablation for liver cancer

LZ Niu, JL Li, KC Xu - Journal of clinical and translational …, 2014 - ncbi.nlm.nih.gov
Based on the primary tumor site, liver cancer can be divided into two categories:(1) primary
liver cancer and (2) metastatic cancer to the liver from a distant primary site. Guided …

Optimization of probe separation distance and cooling time in multi-probe cryoablation technique by arranging probes in triangular and square pattern-A …

G Boregowda, P Mariappan - arXiv preprint arXiv:2309.09959, 2023 - arxiv.org
Cryoablation is a minimally invasive and efficient therapy option for liver cancer. Liquid
nitrogen was used to kill the unwanted cells via freezing. One of the challenges of …

Cryoablation induces necrosis and apoptosis in lung adenocarcinoma in mice

JY Wen, YY Duan, YK Zou, Z Nie… - … in cancer research …, 2007 - journals.sagepub.com
This study evaluated cryoablation on subcutaneously transplanted tumors of lung
adenocarcinoma LA795 in T739 mice in vivo, in an effort to assess the feasibility of …

3D Modelling on Biodegradable Nanoparticle-enhanced Cryoablation of Liver Tumor Based on Real Anatomical Model

S Xu, Z He, Y Zhou, J Liu - Cryoletters, 2016 - ingentaconnect.com
BACKGROUND: Nanoparticle-enhanced freezing is of great importance for developing a
conformal targeted cryoablation for liver tumor with complex shape. However, the safety and …

[HTML][HTML] Liquid Nitrogen-Based Cryoablation in In Vivo Porcine Tissue: A Pilot Study

D Chang, P Mohan, A Amin… - Asian Pacific journal …, 2020 - ncbi.nlm.nih.gov
Methods: Ablations were performed under ultrasound guidance in 4 Yorkshire pigs. The
target lesion cross-section width (W) and depth (D) were 1 cm for liver (n= 8), kidney (n= 4) …

Finite-Element Analysis of Ex Vivo and In Vivo Hepatic Cryoablation

C Kim, AP O'Rourke, DM Mahvi… - IEEE transactions on …, 2007 - ieeexplore.ieee.org
Cryoablation is a widely used method for the treatment of nonresectable primary and
metastatic liver tumors. A model that can accurately predict the size of a cryolesion may …

Anticancer drugs are synergistic with freezing in induction of apoptosis in HCC cells

FJ Yuan, W Zhou, J Zhang, Z Zhang, C Zou, L Huang… - Cryobiology, 2008 - Elsevier
Cryotherapy has been shown to be an important therapeutic alternative to surgery in the
treatment of hepatocellular carcinoma (HCC). Here, the influence of cryo-chemotherapy on …