Pharmacological treatment of COPD: the devil is always in the detail

D Singh, PJ Barnes, R Stockley… - European …, 2018 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is a heterogeneous condition with
considerable pathophysiological and clinical variability across patients [1]. For this reason …

Stable COPD treatment: where are we?

N Roche - COPD: Journal of Chronic Obstructive Pulmonary …, 2018 - Taylor & Francis
The number of pharmacological treatments available for COPD has increased markedly in
the last years, mostly corresponding to new agents, combinations and devices within know …

Effectiveness versus efficacy trials in COPD: how study design influences outcomes and applicability

A Woodcock, I Boucot, DA Leather… - European …, 2018 - Eur Respiratory Soc
Guidelines for chronic obstructive pulmonary disease (COPD) management are based
largely on results from double-blind randomised controlled trials (RCTs) of efficacy. These …

Summary for clinicians: clinical practice guideline on pharmacologic management of chronic obstructive pulmonary disease

EJ Gartman, SS Mulpuru, MJ Mammen… - Annals of the …, 2021 - atsjournals.org
Evidence-based guidelines for the pharmacological management of chronic obstructive
pulmonary disease (COPD) were updated in 2020 by a multidisciplinary panel of experts (1) …

Guidelines for chronic obstructive pulmonary disease treatment and issues of implementation

KF Rabe - Proceedings of the American Thoracic Society, 2006 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
worldwide. Treatment advances over the last decade, although limited, have precipitated the …

Patient-reported outcomes (PROs) in COPD clinical trials: trends and gaps

N Afroz, FS Gutzwiller, AJ Mackay… - … Journal of Chronic …, 2020 - Taylor & Francis
Key characteristics of chronic obstructive pulmonary disease (COPD) that significantly affect
health-related quality of life (HRQoL) include chest symptoms, dyspnea, cough, sputum …

[HTML][HTML] Pharmacological treatment for COPD; GOLD 2017 changes direction

D Singh - British journal of clinical pharmacology, 2017 - ncbi.nlm.nih.gov
The Global initiative for chronic Obstructive Lung Disease (GOLD) strategy document
provides recommendations for the diagnosis, management and prevention of chronic …

Update in chronic obstructive pulmonary disease 2013

E Barreiro, GJ Criner - American journal of respiratory and critical …, 2014 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality
worldwide (1). The revised Global Initiative for Chronic Obstructive Lung Disease (GOLD) …

Year in review 2014: COPD

RD Restrepo - Respiratory care, 2015 - rc.rcjournal.com
Clinicians responsible for treating pulmonary disease often encounter challenges in the
management of patients with COPD. This is due in part to the number of drugs now available …

Multicenter study comparing case definitions used to identify patients with chronic obstructive pulmonary disease

V Prieto-Centurion, AJ Rolle, DH Au… - American Journal of …, 2014 - atsjournals.org
Rationale: Clinical trials in chronic obstructive pulmonary disease (COPD) usually require
evidence of airflow obstruction and clinical risk factors. International Classification of …