PFOA and PFOS disrupt the generation of human pancreatic progenitor cells

S Liu, N Yin, F Faiola - Environmental Science & Technology …, 2018 - ACS Publications
The two most infamous perfluoroalkyl acids, PFOA and PFOS, are persistent, widespread,
bioaccumulative, and associated with many health issues. However, knowledge about their …

Effects of per-and poly-fluorinated alkyl substances on pancreatic and endocrine differentiation of human pluripotent stem cells

S Liu, R Yang, N Yin, F Faiola - Chemosphere, 2020 - Elsevier
Perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) are typical per-and
poly-fluorinated alkyl substances (PFASs) that epidemiological studies have already …

Embryonic exposures to perfluorooctanesulfonic acid (PFOS) disrupt pancreatic organogenesis in the zebrafish, Danio rerio

KE Sant, HM Jacobs, KA Borofski, JB Moss… - Environmental …, 2017 - Elsevier
Perfluorooctanesulfonic acid (PFOS) is a ubiquitous environmental contaminant, previously
utilized as a non-stick application for consumer products and firefighting foam. It can cross …

Perfluorooctanoic acid (PFOA) affects distinct molecular signalling pathways in human primary hepatocytes

T Buhrke, E Krüger, S Pevny, M Rößler, K Bitter… - Toxicology, 2015 - Elsevier
Perfluorooctanoic acid (PFOA) was shown to damage the liver of rodents and to impair
embryonic development. At the molecular level, the hepatotoxic effects were attributed to the …

Prenatal exposure to perfluorooctanoic acid induces nerve growth factor expression in cerebral cortex cells of mouse offspring

X Qin, G Xie, X Wu, X Xu, M Su, B Yang - Environmental Science and …, 2018 - Springer
Previous studies have showed perfluorooctanoic acid (PFOA) inducing cytotoxicity in an
organ. In addition, epidemiological data show that high level of PFOA in cord blood of a …

[HTML][HTML] Developmental effects of PFOS, PFOA and GenX in a 3D human induced pluripotent stem cell differentiation model

N Davidsen, AK Rosenmai, K Lauschke, T Svingen… - Chemosphere, 2021 - Elsevier
Polyfluoroalkyl substances (PFASs), including perfluorooctanesulfonic acid (PFOS) and
perfluorooctanoic acid (PFOA), are persistent pollutants routinely found in human blood …

Effect of prenatal PFOS exposure on liver cell function in neonatal mice

X Liang, G Xie, X Wu, M Su, B Yang - Environmental Science and …, 2019 - Springer
Perfluorooctane sulfonate (PFOS), a hepatotoxic pollutant, is detected in the human cord
blood, and it may induce health risk to an embryo. In this study, we established intrauterine …

Effects of In Utero PFOS Exposure on Epigenetics and Metabolism in Mouse Fetal Livers

TC Ho, HT Wan, WK Lee, TKY Lam, X Lin… - Environmental …, 2023 - ACS Publications
Prenatal exposure to perfluorooctanesulfonate (PFOS) increases fetus' metabolic risk;
however, the investigation of the underlying mechanism is limited. In this study, pregnant …

Developmental toxicity of perfluorononanoic acid in mice

KP Das, BE Grey, MB Rosen, CR Wood… - Reproductive …, 2015 - Elsevier
Perfluorononanoic acid (PFNA) is a ubiquitous and persistent environmental contaminant.
Although its levels in the environment and in humans are lower than those of …

Low dose perfluorooctanoate exposure promotes cell proliferation in a human non-tumor liver cell line

H Zhang, R Cui, X Guo, J Hu, J Dai - Journal of hazardous materials, 2016 - Elsevier
Perfluorooctanoate (PFOA) is a well-known persistent organic pollutant widely found in the
environment, wildlife and humans. Medical surveillance and experimental studies have …