Further understanding of neuro-immune interactions in allergy: implications in pathophysiology and role in disease progression

GN Konstantinou, GN Konstantinou… - Journal of Asthma …, 2022 - Taylor & Francis
The complicated interaction between the central and the autonomic (sympathetic,
parasympathetic, and enteric) nervous systems on the one hand and the immune system …

Neuro-immune interactions in allergic diseases: novel targets for therapeutics

T Voisin, A Bouvier, IM Chiu - International Immunology, 2017 - academic.oup.com
Recent studies have highlighted an emerging role for neuro-immune interactions in
mediating allergic diseases. Allergies are caused by an overactive immune response to a …

New aspects of neuroinflammation and neuroimmune crosstalk in the airways

C Nassenstein, G Krasteva-Christ, H Renz - Journal of Allergy and Clinical …, 2018 - Elsevier
Neuroimmune interaction has long been discussed in the pathogenesis of allergic airway
diseases, such as allergic asthma. Mediators released during inflammation can alter the …

[HTML][HTML] Neural integration and allergic disease

BJ Undem, R Kajekar, DD Hunter, AC Myers - Journal of Allergy and …, 2000 - Elsevier
Changes in neural activity play a key role in many symptoms of allergic disease, including
sneezing, coughing, itching, and ocular irritation, among others. The mechanisms …

Mechanisms underlying the neuronal-based symptoms of allergy

BJ Undem, T Taylor-Clark - Journal of allergy and clinical immunology, 2014 - Elsevier
Persons with allergies present with symptoms that often are the result of alterations in the
nervous system. Neuronally based symptoms depend on the organ in which the allergic …

Neuroimmune interplay during type 2 inflammation: symptoms, mechanisms and therapeutic targets in atopic diseases

B Kim, ME Rothenberg, X Sun, C Bachert… - Journal of Allergy and …, 2023 - Elsevier
Type 2 inflammation is characterized by overexpression and heightened activity of type 2
cytokines, mediators and cells that drive neuroimmune activation and sensitization to …

[HTML][HTML] Neuroimmune communication in allergic rhinitis

Y Zhou, R Chen, L Kong, Y Sun, J Deng - Frontiers in Neurology, 2023 - frontiersin.org
The prevalence rate of allergic rhinitis (AR) is high worldwide. The inhalation of allergens
induces AR, which is an immunoglobulin E-mediated and type 2 inflammation-driven …

The nervous system as a critical regulator of immune responses underlying allergy

P Forsythe - Current pharmaceutical design, 2012 - ingentaconnect.com
The nervous and immune systems collaborate in the control of homeostasis and host
defence. All divisions of the nervous system, sympathetic, parasympathetic and sensory, act …

[HTML][HTML] Neuro-immune crosstalk and allergic inflammation

H Kabata, D Artis - The Journal of Clinical Investigation, 2019 - Am Soc Clin Investig
The neuronal and immune systems exhibit bidirectional interactions that play a critical role in
tissue homeostasis, infection, and inflammation. Neuron-derived neuropeptides and …

Neural pathways in allergic inflammation

L Mirotti, J Castro, FA Costa-Pinto, M Russo - Journal of allergy, 2010 - Wiley Online Library
Allergy is on the rise worldwide. Asthma, food allergy, dermatitis, and systemic anaphylaxis
are amongst the most common allergic diseases. The association between allergy and …