Role of acetylcholine and gabaergic inhibitory transmission in seizure pattern generation in neural networks integrating the neocortex, hippocampus, basal ganglia …

IG Silkis - Neurochemical Journal, 2020 - Springer
We have analyzed the influence of acetylcholine and GABAergic inhibitory transmission on
the functioning of parallel topically organized cortico-basal ganglia–thalamo-cortical neural …

Functional organization of the circuits connecting the cerebral cortex and the basal ganglia: implications for the role of the basal ganglia in epilepsy

SJ Slaght, T Paz, S Mahon, N Maurice… - Epileptic …, 2002 - Wiley Online Library
The basal ganglia are composed of a set of forebrain structures implicated in the adaptive
control of behaviour. These structures process information originating from the entire …

Functional and morphological changes in the hippocampal neuronal circuits associated with epileptic seizures

E Maru, M Kanda, H Ashida - Epilepsia, 2002 - Wiley Online Library
Purpose: We review what is currently known about functional and morphologic plasticity of
hippocampal neuronal circuits in animal epilepsy models. Results: Perforant‐path kindling …

Pattern and pharmacology of propagating epileptiform activity in mouse cerebral cortex

M Alefeld, B Sutor, HJ Luhmann - Experimental neurology, 1998 - Elsevier
Multiple extracellular recording electrodes were used to study the intra-and interhemispheric
spread of stimulus-evoked epileptiform responses in adult mouse neocortical slices. Bath …

Alterations in GABAA Receptor Mediated Inhibition in Adjacent Dorsal Midline Thalamic Nuclei in a Rat Model of Chronic Limbic Epilepsy

K Rajasekaran, J Kapur… - Journal of …, 2007 - journals.physiology.org
There is evidence that the dorsal midline thalamus is involved in the seizures of limbic
epilepsy. However, little is known about the inhibitory synaptic function in this region. In the …

Network dynamics during the progression of seizure-like events in the hippocampal–parahippocampal regions

D Boido, N Jesuthasan, M de Curtis, L Uva - Cerebral Cortex, 2014 - academic.oup.com
Seizure patterns in temporal lobe epilepsies have been described both in humans and in
animal models. The involvement of specific hippocampal–parahippocampal subregions in …

Neural networks in generalized epilepsy and novel antiepileptic drugs

FM Werner, R Coveñas - Current pharmaceutical design, 2019 - ingentaconnect.com
Background: In previous works, alterations of neurotransmitters and neuropeptides in the
brain areas involved in generalized epilepsy have been reported. Objective: We reviewed …

The role of the basal ganglia in the control of seizure

J Vuong, A Devergnas - Journal of Neural Transmission, 2018 - Springer
Epilepsy is a network disorder and each type of seizure involves distinct cortical and
subcortical network, differently implicated in the control and propagation of the ictal activity …

Regulation and control roles of the basal ganglia in the development of absence epileptiform activities

B Hu, D Wang, Z Xia, A Yang, J Zhang, Q Shi… - Cognitive …, 2020 - Springer
Absence epileptiform activities are traditionally considered to be primarily induced by
abnormal interactions between the cortical and thalamic neurons, which form the …

[引用][C] Influence of GABAergic neurons and other neurotransmitters and neuropeptides on ictogenesis in generalized epilepsy

FM Werner, R Coveñas - 2017 - Elsevier