Protective Effects of (E)-β-Caryophyllene (BCP) in Chronic Inflammation

R Scandiffio, F Geddo, E Cottone, G Querio… - Nutrients, 2020 - mdpi.com
(E)-β-caryophyllene (BCP) is a bicyclic sesquiterpene widely distributed in the plant
kingdom, where it contributes a unique aroma to essential oils and has a pivotal role in the …

Therapeutic potential of β-caryophyllene: a dietary cannabinoid in diabetes and associated complications

HM Hashiesh, MFN Meeran, C Sharma, B Sadek… - Nutrients, 2020 - mdpi.com
Diabetes mellitus (DM), a metabolic disorder is one of the most prevalent chronic diseases
worldwide across developed as well as developing nations. Hyperglycemia is the core …

β-Caryophyllene: a sesquiterpene with countless biological properties

F Francomano, A Caruso, A Barbarossa, A Fazio… - Applied sciences, 2019 - mdpi.com
β-Caryophyllene (BCP), a natural bicyclic sesquiterpene, is a selective phytocannabinoid
agonist of type 2 receptors (CB2-R). It isn't psychogenic due to the absence of an affinity to …

Beta-caryophyllene protects against diet-induced dyslipidemia and vascular inflammation in rats: Involvement of CB2 and PPAR-γ receptors

DA Youssef, HM El-Fayoumi, MF Mahmoud - Chemico-Biological …, 2019 - Elsevier
Beta-caryophyllene (BCP) is a phytocannabinoid possessing selective agonistic activity to
cannabinoid type-2 receptors (CB2R) and peroxisome proliferator-activated receptors-α …

[HTML][HTML] A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of β-caryophyllene, a dietary cannabinoid

HM Hashiesh, C Sharma, SN Goyal, B Sadek… - Biomedicine & …, 2021 - Elsevier
The endocannabinoid system (ECS), a conserved physiological system emerged as a novel
pharmacological target for its significant role and potential therapeutic benefits ranging from …

Polypharmacological properties and therapeutic potential of β-caryophyllene: a dietary phytocannabinoid of pharmaceutical promise

C Sharma, JM Al Kaabi, SM Nurulain… - Current …, 2016 - ingentaconnect.com
Background: β-Caryophyllene (BCP) is a natural bicyclic sesquiterpene abundantly found in
essential oils from various spices, fruits and medicinal as well as ornamental plants. It is …

Beta-caryophyllene is a dietary cannabinoid

J Gertsch, M Leonti, S Raduner… - Proceedings of the …, 2008 - National Acad Sciences
The psychoactive cannabinoids from Cannabis sativa L. and the arachidonic acid-derived
endocannabinoids are nonselective natural ligands for cannabinoid receptor type 1 (CB1) …

β‐Caryophyllene protects against alcoholic steatohepatitis by attenuating inflammation and metabolic dysregulation in mice

ZV Varga, C Matyas, K Erdelyi, R Cinar… - British journal of …, 2018 - Wiley Online Library
Background and Aims β‐Caryophyllene (BCP) is a plant‐derived FDA approved food
additive with anti‐inflammatory properties. Some of its beneficial effects in vivo are reported …

A mechanistic review on immunomodulatory effects of selective type two cannabinoid receptor β‐caryophyllene

V Baradaran Rahimi, VR Askari - Biofactors, 2022 - Wiley Online Library
Abstract β‐Caryophyllene (BCP) is a plant‐derived compound and occurs naturally in
various foods and spices, including cinnamon, citrus, fruits, clove, curry, and pepper. BCP …

[HTML][HTML] Beta-caryophyllene alleviates diet-induced neurobehavioral changes in rats: The role of CB2 and PPAR-γ receptors

DA Youssef, HM El-Fayoumi, MF Mahmoud - Biomedicine & …, 2019 - Elsevier
Background and purpose: Insulin resistance (IR) and obesity predispose diseases such as
diabetes, cardiovascular and neurodegenerative disorders. Beta-caryophyllene (BCP), a …